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A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists
NCT06033950 · View on ClinicalTrials.gov ↗
Study Summary
Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients with heart failure and reduced ejection fraction (HFrEF) who are intolerant or ineligible to receive treatment with steroidal mineralocorticoid receptor antagonists (sMRA).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Finerenone
Study Locations (8)
Alabama
- FIN-10004 Fairhope, AL Investigational Site — Fairhope
California
- FIN-10075 San Diego, CA Investigational Site — San Diego
Missouri
- FIN-10002 Kansas City, MO Investigational Site — Kansas City
Texas
- FIN-10015 Austin, TX Investigational Site — Austin
Goiás
- FIN-21003 Goiania, Goias Investigational Site — Goiânia
Sap Paulo
- FIN-21049 Sao Paulo, Investigational Site — Sao Paulp
São Paulo
- FIN-21004 Braganca Paulista, Investigational Site — Bragança Paulista
British Columbia
- FIN-11012 Surrey, BC Investigational Site — Surrey
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,600 participants |
| Start Date | 2024-08-20 |
| Est. Completion | 2028-04 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06033950
The ClinicalTrials.gov registry entry for NCT06033950 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2,600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Colorado Prevention Center, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06033950 reports 8 study locations spanning 8 distinct geographic areas — top geographies include Alabama, California, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06033950 about?
NCT06033950 is a clinical study titled "A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists". Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients with heart failure and reduced ejection fraction (HFrEF) who are intolerant or ineligible to receive treatment with steroidal mineralocorticoid receptor antagonists (sMRA).
What is the current status of trial NCT06033950?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 2,600 participants. The study started on 2024-08-20. Estimated completion is 2028-04.
What conditions does trial NCT06033950 study?
This clinical trial studies the following conditions: Heart Failure. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06033950?
The interventions under investigation include: Placebo (DRUG), Finerenone (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06033950?
This trial is sponsored by Colorado Prevention Center, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06033950 being conducted?
This trial has 8 study locations across Alabama, California, Missouri, Texas, Goiás. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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