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NCT06963476 · ClinicalTrials.gov registry record · NA
rTMS as Add on Treatment for Substance Use Disorders
A NA study of Alcohol Use Disorder and Opioid Use, sponsored by Yale University.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT06963476: Recruiting NA study of Alcohol Use Disorder and Opioid Use, sponsored by Yale University.
NCT06963476 is a NA study of Alcohol Use Disorder and Opioid Use that is actively recruiting participants, run by Yale University. The registered enrollment target is 80 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06963476, a NA study of Alcohol Use Disorder and Opioid Use, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
This pilot study is designed to test feasibility and superiority of rTMS types and target locations for the optimal rTMS intervention for individuals seeking treatment for Alcohol Use Disorder (AUD) or Opioid Use Disorder (OUD). The critical questions this study seeks to answer are: which rTMS type applied to l-dlPFC in OUD participants will induce the greatest reduction of opioid use post-treatment? Is inhibitory rTMS applied to medial prefrontal cortex (mPFC) more effective than excitatory rTMS applied to l-dlPFC at reducing alcohol use post treatment in AUD participants?
Primary Outcome
Successful completion of the study is defined as completing the rTMS protocol and the 4-week post-treatment follow-up.
Conditions Studied
Interventions
- DEVICE repetitive transcranial magnetic stimulation (rTMS) for AUD
- DEVICE repetitive transcranial magnetic stimulation (rTMS) for OUD
Study Locations (1)
Connecticut
- Hartford Healthcare - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-05-12 |
| Est. Completion | 2026-05 |
| Phase | NA |
What NCT06963476 shows while recruiting
NCT06963476 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (76% lower).
The record links to 2 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which repetitive transcranial magnetic stimulation (rTMS) for AUD is the first listed.
NCT06963476 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT06963476 about?
NCT06963476 is a clinical study titled "rTMS as Add on Treatment for Substance Use Disorders". This pilot study is designed to test feasibility and superiority of rTMS types and target locations for the optimal rTMS intervention for individuals seeking treatment for Alcohol Use Disorder (AUD) or Opioid Use Disorder (OUD). The critical questions this study seeks to answer are: which rTMS type...
What is the current status of trial NCT06963476?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2025-05-12. Estimated completion is 2026-05.
What conditions does trial NCT06963476 study?
This clinical trial studies the following conditions: Alcohol Use Disorder, Opioid Use.
What interventions are being tested in trial NCT06963476?
The interventions under investigation include: repetitive transcranial magnetic stimulation (rTMS) for AUD (DEVICE), repetitive transcranial magnetic stimulation (rTMS) for OUD (DEVICE).
Who is sponsoring clinical trial NCT06963476?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06963476 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06963476's enrollment target sits among peer trials
80 100th of 184 higher than 79 of 184 other Alcohol Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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