Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 26 recruiting now official registry

Vascular Diseases clinical trials

Every US clinical trial registered for Vascular Diseases — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

41 US clinical trials · 26 currently recruiting

The research picture

Vascular Diseases has 41 registered US clinical trials, 26 of them open to new participants right now — about 63% of the total.

26
recruiting participants now
63%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
5
top sponsor: ReCor Medical

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 5,000 participants

Factors Affect Outcomes in Cardiovascular Surgery

University of California, Davis

NCT01932411

RECRUITING 4,000 participants

Natural History of Stroke: Cause and Development

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00009243

RECRUITING 1,000 participants

Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

Medtronic Vascular

NCT07174622

RECRUITING 1,000 participants

The RADIANCE CED Study

ReCor Medical

NCT07231757

RECRUITING 1,000 participants

Thrombosis and Inflammation in Vessels Initiative (TIVI)

National Heart, Lung, and Blood Institute (NHLBI)

NCT06552767

RECRUITING 1,000 participants

Global Paradise System US Post Approval Study

ReCor Medical

NCT06297291

RECRUITING NA 1,000 participants

Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

AliveCor

NCT06271577

RECRUITING NA 700 participants

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Fundación EPIC

NCT07286578

RECRUITING NA 454 participants

Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial

University of Pittsburgh

NCT05655936

RECRUITING 450 participants

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

National Institute of Neurological Disorders and Stroke (NINDS)

NCT06615973

RECRUITING NA 259 participants

CLOSM Trial: Groin Closure Using Layered Option for Suture Material

The Cleveland Clinic

NCT06990425

RECRUITING NA 177 participants

Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

C5 Biomedical

NCT06674980

RECRUITING NA 175 participants

SPYRAL GEMINI Pilot Study

Medtronic Vascular

NCT06907147

RECRUITING Phase 4 170 participants

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery

Vanderbilt University Medical Center

NCT05812755

RECRUITING 166 participants

Mechanisms of Pregnancy Vascular Adaptations

University of Wisconsin, Madison

NCT03806283

RECRUITING Phase 4 120 participants

Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients

University of Colorado, Denver

NCT05005793

RECRUITING Phase 2 118 participants

Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD

University of Colorado, Denver

NCT04040959

RECRUITING Phase 1 81 participants

A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

OriCell Therapeutics Co.

NCT06271252

RECRUITING Phase 4 80 participants

Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients

University of Colorado, Denver

NCT06140537

RECRUITING Phase 4 60 participants

Treatment With Aspirin After Preeclampsia: TAP Trial

Malamo Countouris

NCT06281665

RECRUITING NA 55 participants

Passive Limb Movement Study

Medical College of Wisconsin

NCT05935670

RECRUITING NA 50 participants

Improving Blood Pressure Control in Stroke Patients by Increasing Access to a Home Blood Pressure Monitor

Stanford University

NCT05730465

RECRUITING Early Phase 1 50 participants

Sildenafil to Reduce Vascular Remodeling During Left Ventricular Assist Device Support

Montefiore Medical Center

NCT06510322

RECRUITING 25 participants

Diabetic Neuropathy in Spinal Cord Stimulator Patients

University of Chicago

NCT04687215

RECRUITING NA 20 participants

Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc

University of California, Davis

NCT05236374

RECRUITING Phase 2 20 participants

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

Pulmovant

NCT07333183

ACTIVE NOT RECRUITING NA 1,300 participants

SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Medtronic Vascular

NCT05198674

ACTIVE NOT RECRUITING NA 300 participants

RADIANCE Continued Access Protocol

ReCor Medical

NCT05017935

ACTIVE NOT RECRUITING NA 282 participants

A Study of the ReCor Medical Paradise System in Clinical Hypertension

ReCor Medical

NCT02649426

ACTIVE NOT RECRUITING NA 225 participants

The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

ReCor Medical

NCT03614260

ACTIVE NOT RECRUITING Phase 2 135 participants

A Study of Mosliciguat in PH-ILD

Pulmovant

NCT06635850

ACTIVE NOT RECRUITING NA 130 participants

Aventus Thrombectomy System Pulmonary Embolism Clinical Study

Inquis Medical

NCT05907564

ACTIVE NOT RECRUITING NA 60 participants

Sleep and Vascular Health Study

Auburn University

NCT05918744

COMPLETED 1,635 participants

The Clinical and Economic Impact of Pharmacogenomic Testing of Warfarin Therapy in Typical Community Practice Settings

Medco Health Solutions

NCT00830570

COMPLETED NA 574 participants

Targeting of UnControlled Hypertension in Emergency Department

University of Illinois at Chicago

NCT03749499

COMPLETED NA 340 participants

pRESET for Occlusive Stroke Treatment

phenox

NCT03994822

COMPLETED 100 participants

Distributed Registry

Stanford University

NCT03898570

COMPLETED 59 participants

11C-PIB PET Study in MESA at Columbia University

José A. Luchsinger

NCT03981380

COMPLETED NA 50 participants

Vialize Use for the Reduction of Vascular Groin Incisional Dehiscence and Infection

University of Florida

NCT06032949

COMPLETED Phase 4 25 participants

Effect of Thiazolidinedione Treatment Vascular Risk Markers

University of Arkansas

NCT00571506

COMPLETED NA 8 participants

Comparison of Time-Restricted Feeding Versus Grazing

Pennington Biomedical Research Center

NCT01895179

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 3
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Vascular Diseases Trial Landscape

ClinicalTrials.gov lists 41 US studies indexed under Vascular Diseases, and 26 of those are currently open to recruitment — roughly 63% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Vascular Diseases shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Vascular Diseases is led by ReCor Medical with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 41 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Vascular Diseases?

PlainTrial tracks 41 US clinical trials for Vascular Diseases, of which 26 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Vascular Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →