Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06641297 · ClinicalTrials.gov registry record · NA
White Matter Plasticity in Schizophrenia
A NA study of Schizophrenia Disorders, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- NA
- Development phase
- 36
- Enrollment target
- 2
- Study locations
NCT06641297: Recruiting NA study of Schizophrenia Disorders, sponsored by University of Maryland, Baltimore.
NCT06641297 is a NA study of Schizophrenia Disorders that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 36 participants, below the 133-participant average among 5 other Schizophrenia Disorders trials with a reported enrollment target (73% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06641297, a NA study of Schizophrenia Disorders, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
- 2
- Study locations
Study Summary
Schizophrenia spectrum disorders are associated with impairment in the microstructure of white matter, the key brain tissue responsible for fast communication between different brain regions necessary for any complex task. This white matter impairment is linked to problems with cognition in schizophrenia, especially slower processing speed. This project aims to study the potential for correcting white matter deficits in schizophrenia by examining mechanisms underlying white matter structure changes in response to training on playing a mock musical instrument.
Primary Outcome
fractional anisotropy of white matter tracts as assessed with diffusion tensor imaging
Conditions Studied
Interventions
- BEHAVIORAL Music video game
Study Locations (2)
Maryland
- Maryland Psychiatric Research Center - Catonsville
- University of Maryland Baltimore - Maryland Psychiatric Research Center - Catonsville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2025-01-02 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT06641297 shows while recruiting
NCT06641297 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 133-participant average among 5 other Schizophrenia Disorders trials with a reported enrollment target (73% lower).
The record links to 1 condition, with Schizophrenia Disorders appearing as the primary indexed condition, and to 1 intervention - of which Music video game is the first listed.
NCT06641297 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06641297 about?
NCT06641297 is a clinical study titled "White Matter Plasticity in Schizophrenia". Schizophrenia spectrum disorders are associated with impairment in the microstructure of white matter, the key brain tissue responsible for fast communication between different brain regions necessary for any complex task. This white matter impairment is linked to problems with cognition in schizoph...
What is the current status of trial NCT06641297?
This trial is currently recruiting. It is a NA study. The enrollment target is 36 participants. The study started on 2025-01-02. Estimated completion is 2026-12-31.
What conditions does trial NCT06641297 study?
This clinical trial studies the following conditions: Schizophrenia Disorders.
What interventions are being tested in trial NCT06641297?
The interventions under investigation include: Music video game (BEHAVIORAL).
Who is sponsoring clinical trial NCT06641297?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06641297 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia Disorders
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Volatility in Paranoia (VIP) Trial: An RCT of Changes in Volatility With Psychotherapy
RECRUITING · NA
-
Visual Perception in Schizophrenia
RECRUITING · NA
-
Brain Stimulation to the Hippocampus in Schizophrenia
RECRUITING · NA
-
Activities to Change Your Mood: A Test of the Acceptability and Initial Efficacy in Clinical Samples and Healthy Controls
RECRUITING · NA
-
Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00929006 · 36 participants · Early Phase 1
Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism
- NCT01891318 · 36 participants · Phase 1
Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study
- NCT02291848 · 36 participants · Phase 1
Tumor-Associated Antigen-Specific Cytotoxic T-Lymphocytes for Multiple Myeloma
- NCT02366819 · 36 participants · Phase 4
Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI