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NCT06544291 · ClinicalTrials.gov registry record · Phase 2

Combined THC and CBD for OUD and Chronic Pain

A Phase 2 study of Chronic Pain and Opioid Use Disorder, sponsored by Yale University.

Recruiting
Registry status
Phase 2
Development phase
147
Enrollment target
1
Study location

NCT06544291 is a Phase 2 study of Chronic Pain and Opioid Use Disorder that is actively recruiting participants, run by Yale University. The registered enrollment target is 147 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06544291, a Phase 2 study of Chronic Pain and Opioid Use Disorder, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
Phase 2
Development phase
147 participants
Enrollment target
1
Study location

Study Summary

The primary objective of this phase 2 study is to investigate the therapeutic potential of orally administered combined delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in relieving both pain and cue-induced opioid craving in people with co-occurring opioid use disorder (OUD) and chronic pain who are undergoing methadone therapy.

Conditions Studied

Chronic Pain Opioid Use Disorder

Interventions

  • DRUG CBD 300mg
  • DRUG CBD 600mg
  • DRUG Placebo 0mg

Study Locations (1)

Connecticut

  • Connecticut Mental Health Center - New Haven

Trial Details

FieldValue
Enrollment Target 147 participants
Start Date 2024-10-22
Est. Completion 2028-01-28
Phase Phase 2

Sponsor

Yale University

1,492 total trials

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What the Registry Record Tells You About NCT06544291

The ClinicalTrials.gov registry entry for NCT06544291 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 147 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (81% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 3 interventions - of which CBD 300mg is the first listed.

NCT06544291 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT06544291 about?

NCT06544291 is a clinical study titled "Combined THC and CBD for OUD and Chronic Pain". The primary objective of this phase 2 study is to investigate the therapeutic potential of orally administered combined delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in relieving both pain and cue-induced opioid craving in people with co-occurring opioid use disorder (OUD) and chronic pai...

What is the current status of trial NCT06544291?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 147 participants. The study started on 2024-10-22. Estimated completion is 2028-01-28.

What conditions does trial NCT06544291 study?

This clinical trial studies the following conditions: Chronic Pain, Opioid Use Disorder.

What interventions are being tested in trial NCT06544291?

The interventions under investigation include: CBD 300mg (DRUG), CBD 600mg (DRUG), Placebo 0mg (DRUG).

Who is sponsoring clinical trial NCT06544291?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06544291 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.