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NCT06108076 · ClinicalTrials.gov registry record · Early Phase 1
Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes
A Early Phase 1 study of Type 2 Diabetes and Heart Failure, Reduced Ejection Fraction, sponsored by The University of Texas Health Science Center at San Antonio.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT06108076 is a Early Phase 1 study of Type 2 Diabetes and Heart Failure, Reduced Ejection Fraction that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 10 participants, below the 1,103-participant average among 288 other Type 2 Diabetes trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06108076, a Early Phase 1 study of Type 2 Diabetes and Heart Failure, Reduced Ejection Fraction, is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will provide insight into whether cardiac function changes with oral Ketone Esters (KE) administered to patients with Type 2 Diabetes Mellitus (T2DM) and Heart failure with reduced ejection fraction (HFrEF). Plasma ketones are avidly extracted by cardiac muscle and their uptake is not dependent upon insulin or influenced by insulin resistance.
Conditions Studied
Interventions
- DRUG Ketone Monoester (KE)
Study Locations (1)
Texas
- University of Texas Health Science Center at San Antonio - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2024-01-16 |
| Est. Completion | 2026-12-31 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06108076
The ClinicalTrials.gov registry entry for NCT06108076 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,103-participant average among 288 other Type 2 Diabetes trials with a reported enrollment target (99% lower). The listed sponsor is The University of Texas Health Science Center at San Antonio, which has 378 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Type 2 Diabetes appearing as the primary indexed condition, and to 1 intervention - of which Ketone Monoester (KE) is the first listed.
NCT06108076 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06108076 about?
NCT06108076 is a clinical study titled "Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes". This study will provide insight into whether cardiac function changes with oral Ketone Esters (KE) administered to patients with Type 2 Diabetes Mellitus (T2DM) and Heart failure with reduced ejection fraction (HFrEF). Plasma ketones are avidly extracted by cardiac muscle and their uptake is not dep...
What is the current status of trial NCT06108076?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2024-01-16. Estimated completion is 2026-12-31.
What conditions does trial NCT06108076 study?
This clinical trial studies the following conditions: Type 2 Diabetes, Heart Failure, Reduced Ejection Fraction.
What interventions are being tested in trial NCT06108076?
The interventions under investigation include: Ketone Monoester (KE) (DRUG).
Who is sponsoring clinical trial NCT06108076?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06108076 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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