Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED NA

Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

NCT06179290 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of the study is to evaluate changes in biomarkers of exposure (BoE) to harmful and potentially harmful constituents (HPHCs) in adult smokers who completely switch to Ploom heated tobacco products (HTPs) compared to those who continue to smoke usual brand combustible cigarettes (UBCC).

Conditions Studied

Interventions

  • OTHER Ploom HTP Menthol HTS; MX3 (681)
  • OTHER Ploom HTP Tobacco HTS; R8 (120)
  • OTHER Smoking Abstinence (menthol)
  • OTHER Smoking Abstinence (non-menthol)

Study Locations (7)

Arkansas

  • Woodland Research Northwest — Rogers

Kansas

  • Dr. Vince Clinical Research, LLC — Overland Park

Kentucky

  • Alliance for Multispecialty Research, LLC — Lexington

Missouri

  • QPS Bio-Kinetic — Springfield

Nebraska

  • Celerion Lincoln — Lincoln

Tennessee

  • Alliance for Multispecialty Research, LLC — Knoxville

Wisconsin

  • Spaulding Clinical Research — West Bend

Trial Details

FieldValue
Enrollment Target 921 participants
Start Date 2023-10-02
Est. Completion 2025-03-24
Phase NA

Sponsor

Altria Client Services

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06179290

The ClinicalTrials.gov registry entry for NCT06179290 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 921 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Altria Client Services, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Tobacco Use appearing as the primary indexed condition, and to 4 interventions — of which Ploom HTP Menthol HTS; MX3 (681) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06179290 reports 7 study locations spanning 7 distinct geographic areas — top geographies include Arkansas, Kansas, Kentucky. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06179290 about?

NCT06179290 is a clinical study titled "Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products". The purpose of the study is to evaluate changes in biomarkers of exposure (BoE) to harmful and potentially harmful constituents (HPHCs) in adult smokers who completely switch to Ploom heated tobacco products (HTPs) compared to those who continue to smoke usual brand combustible cigarettes (UBCC).

What is the current status of trial NCT06179290?

This trial is currently completed. It is a NA study. The enrollment target is 921 participants. The study started on 2023-10-02. Estimated completion is 2025-03-24.

What conditions does trial NCT06179290 study?

This clinical trial studies the following conditions: Tobacco Use. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06179290?

The interventions under investigation include: Ploom HTP Menthol HTS; MX3 (681) (OTHER), Ploom HTP Tobacco HTS; R8 (120) (OTHER), Smoking Abstinence (menthol) (OTHER), Smoking Abstinence (non-menthol) (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06179290?

This trial is sponsored by Altria Client Services, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06179290 being conducted?

This trial has 7 study locations across Arkansas, Kansas, Kentucky, Missouri, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial