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NCT06058988 · ClinicalTrials.gov registry record · Phase 2

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

A Phase 2 study of Glioblastoma and Metastatic Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
30
Enrollment target
1
Study location

NCT06058988 is a Phase 2 study of Glioblastoma and Metastatic Cancer that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 30 participants, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06058988, a Phase 2 study of Glioblastoma and Metastatic Cancer, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to find out how much tratuzumab deruxtecan (T-DXd) can penetrate the tumor when injected into the body, and whether T-DXd may be an effective treatment for brain cancers that express the HER2 protein.

Interventions

  • DRUG Trastuzumab deruxtecan

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2023-09-22
Est. Completion 2027-09-22
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT06058988

The ClinicalTrials.gov registry entry for NCT06058988 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (72% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Glioblastoma appearing as the primary indexed condition, and to 1 intervention - of which Trastuzumab deruxtecan is the first listed.

NCT06058988 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT06058988 about?

NCT06058988 is a clinical study titled "Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer". The purpose of this study is to find out how much tratuzumab deruxtecan (T-DXd) can penetrate the tumor when injected into the body, and whether T-DXd may be an effective treatment for brain cancers that express the HER2 protein.

What is the current status of trial NCT06058988?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2023-09-22. Estimated completion is 2027-09-22.

What conditions does trial NCT06058988 study?

This clinical trial studies the following conditions: Glioblastoma, Metastatic Cancer, Recurrent Glioblastoma, Brain Cancer, Leptomeningeal Metastasis.

What interventions are being tested in trial NCT06058988?

The interventions under investigation include: Trastuzumab deruxtecan (DRUG).

Who is sponsoring clinical trial NCT06058988?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06058988 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.