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OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis
NCT06355934 · View on ClinicalTrials.gov ↗
Study Summary
The overall aim of this observational study is to generate real-world evidence on the pre- and post-diagnosis disease journeys, including baseline characteristics, treatment patterns and selected clinical, economic, and humanistic outcomes (for example Health Related Quality of Life (HRQoL), Neuropathy impairment score, activities of daily living (ADL) assessments) in patients with ATTR amyloidosis, and to better understand how the disease is presented.
Conditions Studied
Interventions
- OTHER no intervention
Study Locations (20)
Other
- Research Site — Beijing
- Research Site — Changsha
- Research Site — Chengdu
- Research Site — Guangzhou
- Research Site — Wuhan
- Research Site — Horsens
- Research Site — Berlin
- Research Site — Tokyo
- Research Site — Lisbon
- Research Site — Porto
- Research Site — A Coruña
- Research Site — Barcelona
- Research Site — Bilbao
- Research Site — El Palmar
- Research Site — Huelva
- Research Site — Las Palmas de Gran Canaria
- Research Site — Madrid
- Research Site — Majadahonda
Minnesota
- Research Site — Eden Prairie
Alberta
- Research Site — Calgary
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52,121 participants |
| Start Date | 2023-08-21 |
| Est. Completion | 2026-09-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06355934
The ClinicalTrials.gov registry entry for NCT06355934 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 52,121 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,053 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with ATTR Amyloidosis appearing as the primary indexed condition, and to 1 intervention — of which no intervention is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06355934 reports 20 study locations spanning 3 distinct geographic areas — top geographies include Other, Minnesota, Alberta. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06355934 about?
NCT06355934 is a clinical study titled "OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis". The overall aim of this observational study is to generate real-world evidence on the pre- and post-diagnosis disease journeys, including baseline characteristics, treatment patterns and selected clinical, economic, and humanistic outcomes (for example Health Related Quality of Life (HRQoL), Neuropa...
What is the current status of trial NCT06355934?
This trial is currently recruiting. The enrollment target is 52,121 participants. The study started on 2023-08-21. Estimated completion is 2026-09-30.
What conditions does trial NCT06355934 study?
This clinical trial studies the following conditions: ATTR Amyloidosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06355934?
The interventions under investigation include: no intervention (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06355934?
This trial is sponsored by AstraZeneca, which has 1,053 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06355934 being conducted?
This trial has 20 study locations across Minnesota, Alberta. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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