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Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates
NCT06824350 · View on ClinicalTrials.gov ↗
Study Summary
The CLEAN (ChLorine to reduce Enteric and Antibiotic resistant infections in Neonates) cluster randomized controlled trial in western Kenya will evaluate the impact of a multi-component chlorination intervention in health care facilities on maternal and neonatal health. Intervention facilities will receive a passive chlorination technology for water supply treatment and a reliable supply of sodium hypochlorite disinfectant. Both intervention and treatment facilities will receive infection prevention and control messaging. The goal of the study is to evaluate the impact of the intervention on bacterial contamination of water supply, on staff hands, and on high-touch surfaces in maternity wards, and the following outcomes among facility-born neonates and their mothers: (1) gut carriage of bacterial pathogens associated with sepsis one week post-birth, (2) gut carriage of antibiotic resistant bacteria one week post-birth, and (3) symptoms of possible serious bacterial infection one week following birth.
Conditions Studied
Interventions
- DEVICE chlorination for water disinfection and surface disinfection
- BEHAVIORAL infection prevention and control messaging
Study Locations (2)
California
- University of California, Berkeley — Berkeley
Other
- Kenya Medical Research Institute — Nairobi
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45,450 participants |
| Start Date | 2025-01-21 |
| Est. Completion | 2027-07 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06824350
The ClinicalTrials.gov registry entry for NCT06824350 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 45,450 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Berkeley, which has 60 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Sepsis appearing as the primary indexed condition, and to 2 interventions — of which chlorination for water disinfection and surface disinfection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06824350 reports 2 study locations spanning 2 distinct geographic areas — top geographies include California, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06824350 about?
NCT06824350 is a clinical study titled "Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates". The CLEAN (ChLorine to reduce Enteric and Antibiotic resistant infections in Neonates) cluster randomized controlled trial in western Kenya will evaluate the impact of a multi-component chlorination intervention in health care facilities on maternal and neonatal health. Intervention facilities will ...
What is the current status of trial NCT06824350?
This trial is currently recruiting. It is a NA study. The enrollment target is 45,450 participants. The study started on 2025-01-21. Estimated completion is 2027-07.
What conditions does trial NCT06824350 study?
This clinical trial studies the following conditions: Sepsis, Antibiotic Resistant Infection, Neonatal Mortality, Enteric Infections, Serious Bacterial Infection. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06824350?
The interventions under investigation include: chlorination for water disinfection and surface disinfection (DEVICE), infection prevention and control messaging (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06824350?
This trial is sponsored by University of California, Berkeley, which has 60 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06824350 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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