Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05845021 · ClinicalTrials.gov registry record · NA
Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty
A NA study of Osteoporosis and Arthroplasty Complications, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- NA
- Development phase
- 2,000
- Enrollment target
- 1
- Study location
NCT05845021: Recruiting NA study of Osteoporosis and Arthroplasty Complications, sponsored by Johns Hopkins University.
NCT05845021 is a NA study of Osteoporosis and Arthroplasty Complications that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 2,000 participants, above the 1,522-participant average among 84 other Osteoporosis trials with a reported enrollment target (31% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05845021, a NA study of Osteoporosis and Arthroplasty Complications, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- NA
- Development phase
- 2,000 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty. The main question this study aims to answer is: 1\) What is impact of a surgeon-driven bone health referral pathway on implant-related complications and fragility fractures when compared to standard of care primary care provider referral. Researchers will compare the endocrinology referral pathway and standard of care to see if there is a difference in treatment rates, fragility fractures, and implant-related complications following lower extremity arthroplasty.
Primary Outcome
2-year incidence of all-cause revision following lower extremity arthroplasty
Conditions Studied
Interventions
- COMBINATION_PRODUCT Surgeon-Initiated Bone Health Referral Pathway
Study Locations (1)
Maryland
- Charter Professional Center - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 2023-09-27 |
| Est. Completion | 2028-07 |
| Phase | NA |
What NCT05845021 shows while recruiting
NCT05845021 is an interventional study that assigns participants to a tested intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus, above the 1,522-participant average among 84 other Osteoporosis trials with a reported enrollment target (31% higher).
The record links to 3 conditions, with Osteoporosis appearing as the primary indexed condition, and to 1 intervention - of which Surgeon-Initiated Bone Health Referral Pathway is the first listed.
NCT05845021 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05845021 about?
NCT05845021 is a clinical study titled "Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty". The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty. The main question this study aims to answer is: 1\) What is impact of a surgeon-driven bone health referral pathway on implant-related complications and ...
What is the current status of trial NCT05845021?
This trial is currently recruiting. It is a NA study. The enrollment target is 2,000 participants. The study started on 2023-09-27. Estimated completion is 2028-07.
What conditions does trial NCT05845021 study?
This clinical trial studies the following conditions: Osteoporosis, Arthroplasty Complications, Fragility Fracture.
What interventions are being tested in trial NCT05845021?
The interventions under investigation include: Surgeon-Initiated Bone Health Referral Pathway (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT05845021?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05845021 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoporosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05845021's enrollment target sits among peer trials
2,000 10th of 84 higher than 75 of 84 other Osteoporosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoporosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
OsteoPorotic fracTure preventION System (OPTIONS) Research Study
RECRUITING · NA
-
RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE
RECRUITING · NA
-
Mode of Exercise and Bone Biomarkers in Older Veterans
RECRUITING · NA
-
Synbiotic to Attenuate Resorption of the Skeleton
RECRUITING · NA
-
Sickle Cell Disease (SCD) Bone Pain Study
ACTIVE NOT RECRUITING · NA
-
Utility of Cortical Bone Tissue Properties in the Assessment of Fracture Risk
ACTIVE NOT RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00001465 · 2,000 participants
Study of the Disease Process of Lymphangioleiomyomatosis
- NCT00001595 · 2,000 participants
An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
- NCT00138931 · 2,000 participants
Genetics of Cardiovascular and Neuromuscular Disease
- NCT00288119 · 2,000 participants
Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI