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2026 data Public-data reference. official source

Rheumatic Diseases

Open-data reference.

12 US clinical trials · 4 currently recruiting

Active & Recent Trials

RECRUITING 2,000,000 participants

Observational Pharmaco-Epidemiology Research & Analysis

Epividian

NCT03813862

RECRUITING 7,500 participants

Studies of the Natural History of Rheumatic Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00024479

RECRUITING 5,000 participants

Rheumatology Patient Registry and Biorepository

Yale University

NCT04402086

RECRUITING Phase 2 285 participants

A Study of SPY072 in Rheumatic Disease

Spyre Therapeutics

NCT07148414

ACTIVE NOT RECRUITING NA 5,269 participants

Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications

VA Office of Research and Development

NCT02694185

ACTIVE NOT RECRUITING Phase 4 129 participants

The COVID-19 VaccinE Response and Co-Administration in Rheumatology Patients (COVER-CoAd)

Oregon Health and Science University

NCT05543642

ACTIVE NOT RECRUITING NA 89 participants

SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization

CrannMed

NCT06550024

ACTIVE NOT RECRUITING NA 60 participants

Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases

Northwestern University

NCT05822219

ACTIVE NOT RECRUITING NA 60 participants

Impact of Different Exercise Programs on Knee OA

Shirley Ryan AbilityLab

NCT05844124

COMPLETED NA 389 participants

Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia

Children's Hospital Medical Center, Cincinnati

NCT03268421

COMPLETED NA 236 participants

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

Anderson Orthopaedic Research Institute

NCT01121146

COMPLETED NA 230 participants

Marathon and Enduron Polyethylene at Long-Term Follow-up

Anderson Orthopaedic Research Institute

NCT02508428

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Rheumatic Diseases Trial Landscape

ClinicalTrials.gov lists 12 US studies indexed under Rheumatic Diseases, and 4 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Rheumatic Diseases shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Rheumatic Diseases is led by Anderson Orthopaedic Research Institute with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 12 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Rheumatic Diseases?

PlainTrial tracks 12 US clinical trials for Rheumatic Diseases, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Rheumatic Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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