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ClinicalTrials.gov 4 recruiting now full pipeline small index

Rheumatic Diseases: full-pipeline trial registry

4 of 12 indexed Rheumatic Diseases trials are currently recruiting.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 4 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Rheumatic Diseases: 12 US clinical trials tracked, 4 recruiting.

Rheumatic Diseases is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Anderson Orthopaedic Research Institute, running 2 of these trials.

Enrollment posture brief

Registry condition rheumatic-diseases

OPEN 4 | RECR 33% | LATE 1 | EARLY 1 | RANK #1429 | SPON 2

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Rheumatic Diseases (this)33%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Rheumatic Diseases

Rheumatic Diseases lists 4 open slots (33% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Rheumatic Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Rheumatic Diseases is recruiting below its size-band peers.

    4 of 12 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Rheumatic Diseases research.

    Anderson Orthopaedic Research Institute accounts for 2 of 12 trials (16.7%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Typical Rheumatic Diseases enrolment sits around 285 participants.

    Median target enrolment is 285 among the 12 trials that report a genuine target (sentinel values excluded). 3 of those (25%) plan for fewer than 100 participants.

  4. Rheumatic Diseases research is mostly interventional.

    9 interventional and 3 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 41

Open and recent trials

12 total, page 1 of 1

RECRUITING 2,000,000 participants

Observational Pharmaco-Epidemiology Research & Analysis

Epividian

NCT03813862

RECRUITING 7,500 participants

Studies of the Natural History of Rheumatic Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00024479

RECRUITING 5,000 participants

Rheumatology Patient Registry and Biorepository

Yale University

NCT04402086

RECRUITING Phase 2 285 participants

A Study of SPY072 in Rheumatic Disease

Spyre Therapeutics

NCT07148414

ACTIVE NOT RECRUITING NA 5,269 participants

Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications

VA Office of Research and Development

NCT02694185

ACTIVE NOT RECRUITING Phase 4 129 participants

The COVID-19 VaccinE Response and Co-Administration in Rheumatology Patients (COVER-CoAd)

Oregon Health and Science University

NCT05543642

ACTIVE NOT RECRUITING NA 89 participants

SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization

CrannMed

NCT06550024

ACTIVE NOT RECRUITING NA 60 participants

Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases

Northwestern University

NCT05822219

ACTIVE NOT RECRUITING NA 60 participants

Impact of Different Exercise Programs on Knee OA

Shirley Ryan AbilityLab

NCT05844124

COMPLETED NA 389 participants

Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia

Children's Hospital Medical Center, Cincinnati

NCT03268421

COMPLETED NA 236 participants

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

Anderson Orthopaedic Research Institute

NCT01121146

COMPLETED NA 230 participants

Marathon and Enduron Polyethylene at Long-Term Follow-up

Anderson Orthopaedic Research Institute

NCT02508428

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 4 1

Named interventions

Most-linked intervention names on Rheumatic Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Hip Replacement with noncrosslinked Enduron polyethylene Device
1 trials
Hip Replacement with crosslinked Marathon polyethylene Device
1 trials
Graded Aerobic Exercise Behavioral
1 trials
Fibromyalgia Integrative Training for Teens Behavioral
1 trials
Total Hip Replacement Device
1 trials
Diphtheria, pertussis, and tetanus booster vaccine Biological
1 trials
SakuraBead Resorbable Microspheres Device
1 trials
Exercise for Knee Osteoarthritis - (Aquatic Walking) Other
1 trials

US sites by state

Facility locations filed on Rheumatic Diseases trials. A trial with sites in several states counts in each.

Virginia 3 trials
North Carolina 3 trials
Illinois 3 trials
Florida 3 trials
California 3 trials
Texas 2 trials
Pennsylvania 2 trials
Maryland 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Rheumatic Diseases page

12 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Rheumatic Diseases condition card totals 12 registered trials; most-linked intervention Hip Replacement with noncrosslinked Enduron polyethylene; top US site state Virginia. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.