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Liver Cirrhosis Network Cohort Study
NCT05740358 · View on ClinicalTrials.gov ↗
Study Summary
Liver Cirrhosis Network (LCN) Cohort Study is an observational study designed to identify risk factors and develop prediction models for risk of decompensation in adults with liver cirrhosis. LCN Cohort Study involves multiple institutions and an anticipated 1200 participants. Enrolled participants will have study visits every 6 months (180 days), with opportunities to complete specific visit components via telehealth or remotely. Visits will include collection of questionnaire data and the in-person visits will include questionnaires, physical exams, imaging, and sample collection.
Conditions Studied
Study Locations (14)
California
- University of California San Diego NAFLD Research Center — La Jolla
- Keck Medical Center of USC — Los Angeles
- LAC + USC Medical Center — Los Angeles
- UCSF/Zuckerberg San Francisco General Hospital and Trauma Center — San Francisco
- UCSF Medical Center — San Francisco
New York
- New York Presbyterian/Weill Cornell — New York
- Columbia University Iriving School of Medicine — New York
Virginia
- Central Virginia Veterans Healthcare System — Richmond
- Virginia Commonwealth University — Richmond
Florida
- University of Miami Health System — Miami
Michigan
- University of Michigan — Ann Arbor
Minnesota
- Mayo Clinic — Rochester
North Carolina
- Duke Liver Center — Durham
Ohio
- Cleveland Clinic — Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,222 participants |
| Start Date | 2022-11-18 |
| Est. Completion | 2030-10-24 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05740358
The ClinicalTrials.gov registry entry for NCT05740358 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,222 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,033 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Cirrhosis appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05740358 reports 14 study locations spanning 8 distinct geographic areas — top geographies include California, New York, Virginia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05740358 about?
NCT05740358 is a clinical study titled "Liver Cirrhosis Network Cohort Study". Liver Cirrhosis Network (LCN) Cohort Study is an observational study designed to identify risk factors and develop prediction models for risk of decompensation in adults with liver cirrhosis. LCN Cohort Study involves multiple institutions and an anticipated 1200 participants. Enrolled participants ...
What is the current status of trial NCT05740358?
This trial is currently active not recruiting. The enrollment target is 1,222 participants. The study started on 2022-11-18. Estimated completion is 2030-10-24.
What conditions does trial NCT05740358 study?
This clinical trial studies the following conditions: Cirrhosis, Cirrhosis, Liver, Cirrhosis Early, Cirrhosis Due to Hepatitis B, Cirrhosis Advanced. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT05740358?
This trial is sponsored by Northwestern University, which has 1,033 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05740358 being conducted?
This trial has 14 study locations across California, Florida, Michigan, Minnesota, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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