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A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
NCT05827016 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to compare the effectiveness of iberdomide maintenance to lenalidomide maintenance therapy after autologous stem cell transplantation (ASCT) in participants with newly diagnosed multiple myeloma (NDMM).
Conditions Studied
Interventions
- DRUG Lenalidomide
- DRUG Iberdomide
Study Locations (20)
Florida
- Mayo Clinic Florida — Jacksonville
- Tampa General Hospital — Tampa
- H. Lee Moffitt Cancer Center & Research Institute — Tampa
- Cleveland Clinic — Weston
Georgia
- University Cancer Blood Ctr — Athens
- The Winship Cancer Institute of Emory University — Atlanta
- Augusta University - Georgia Cancer Center — Augusta
Michigan
- University of Michigan - Rogel Cancer Center — Ann Arbor
- Henry Ford Health System - The Henry Ford Cancer Institute (HFCI) - Detroit — Detroit
- Cancer & Hematology Centers of Western Michigan (CHCWM) — Grand Rapids
New York
- Local Institution - 0328 — Brooklyn
- Perlmutter Cancer Center at NYU Langone Hematology Oncology Associates-Mineola — Mineola
Colorado
- Rocky Mountain Cancer Centers — Aurora
Illinois
- The University of Chicago Medical Center - Duchossois Center for Advanced Medicine — Chicago
Kansas
- University of Kansas Cancer Center - The Richard and Annette Bloch Cancer Care Pavilion — Westwood
Maryland
- Maryland Oncology Hematology, PA- Clinton — Clinton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,216 participants |
| Start Date | 2023-06-22 |
| Est. Completion | 2036-01-01 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05827016
The ClinicalTrials.gov registry entry for NCT05827016 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,216 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bristol-Myers Squibb, which has 504 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 2 interventions — of which Lenalidomide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05827016 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, Georgia, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05827016 about?
NCT05827016 is a clinical study titled "A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma". The purpose of this study is to compare the effectiveness of iberdomide maintenance to lenalidomide maintenance therapy after autologous stem cell transplantation (ASCT) in participants with newly diagnosed multiple myeloma (NDMM).
What is the current status of trial NCT05827016?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 1,216 participants. The study started on 2023-06-22. Estimated completion is 2036-01-01.
What conditions does trial NCT05827016 study?
This clinical trial studies the following conditions: Multiple Myeloma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05827016?
The interventions under investigation include: Lenalidomide (DRUG), Iberdomide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05827016?
This trial is sponsored by Bristol-Myers Squibb, which has 504 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05827016 being conducted?
This trial has 20 study locations across Colorado, Florida, Georgia, Illinois, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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