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NCT06940479 · ClinicalTrials.gov registry record · NA
Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis
A NA study of Knee Osteoarthritis, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- NA
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT06940479: Recruiting NA study of Knee Osteoarthritis, sponsored by University of Colorado, Denver.
NCT06940479 is a NA study of Knee Osteoarthritis that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 46 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06940479, a NA study of Knee Osteoarthritis, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- NA
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if genicular artery embolization (GAE) can improve knee pain and decrease inflammation in adults with knee osteoarthritis. The main question it aims to answer is: \- Does the GAE procedure improve knee pain and decrease inflammation? Researchers will compare synovial fluid samples taken from the knee before and after the procedure. Participants will: * Have a contrast enhanced MRI before and after the procedure * Complete performance-based measures before and after the procedure * Complete questionnaires before and after the procedure
Primary Outcome
To estimate the correlation between objective changes in synovial fluid biomarkers (IL-6, VEGF and MCP-1) and changes in subjective symptomatic response (KOOS) 3 months after treatment of knee osteoarthritis with GAE. KOOS is a validated knee osteoarthritis scoring system that involves five subscales: pain (9 questions), symptoms (7 questions), activities of daily living (17 questions), sport/recreation (5 questions), knee-related quality of life (4 questions). Trials demonstrate maximum sympt
Conditions Studied
Interventions
- PROCEDURE GAE procedure
Study Locations (1)
Colorado
- University of Colorado Anschutz Medical Campus - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2025-07-16 |
| Est. Completion | 2028-07 |
| Phase | NA |
What NCT06940479 shows while recruiting
NCT06940479 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which GAE procedure is the first listed.
NCT06940479 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT06940479 about?
NCT06940479 is a clinical study titled "Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis". The goal of this clinical trial is to learn if genicular artery embolization (GAE) can improve knee pain and decrease inflammation in adults with knee osteoarthritis. The main question it aims to answer is: \- Does the GAE procedure improve knee pain and decrease inflammation? Researchers will com...
What is the current status of trial NCT06940479?
This trial is currently recruiting. It is a NA study. The enrollment target is 46 participants. The study started on 2025-07-16. Estimated completion is 2028-07.
What conditions does trial NCT06940479 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT06940479?
The interventions under investigation include: GAE procedure (PROCEDURE).
Who is sponsoring clinical trial NCT06940479?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06940479 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06940479's enrollment target sits among peer trials
46 73rd of 101 higher than 28 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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