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NCT04250259 · ClinicalTrials.gov registry record · Phase 2

SAMe Trial for Patients With Alcoholic Cirrhosis

A Phase 2 study of Alcoholic Cirrhosis, sponsored by Indiana University.

Recruiting
Registry status
Phase 2
Development phase
196
Enrollment target
2
Study locations

NCT04250259 is a Phase 2 study of Alcoholic Cirrhosis that is actively recruiting participants, run by Indiana University. The registered enrollment target is 196 participants. The trial reports 2 study locations across 2 states.

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The verdict

NCT04250259, a Phase 2 study of Alcoholic Cirrhosis, is actively recruiting participants, sponsored by Indiana University.

RECRUITING
Registry status
Phase 2
Development phase
196 participants
Enrollment target
2
Study locations

Study Summary

The proposed of this randomized, double blinded, placebo-controlled study is to assess the effect of SAMe compared to placebo in patients with alcoholic cirrhosis Child Class A and B. The primary objective of the study is to test relationship between SAMe (S-adenosylmethionine) supplement on liver function. The hypothesis is that SAMe supplement will improve liver function in patients with alcoholic liver disease. The improvement in liver function will lead to the reduction in all-cause mortality in patients with alcoholic cirrhosis in those who receive SAMe supplement when compared to those receiving placebo.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG SAMe 400 mg tablet

Study Locations (2)

California

  • Cedars-Sinai Medical Center - Los Angeles

Indiana

  • Indiana University Hospital - Indianapolis

Trial Details

FieldValue
Enrollment Target 196 participants
Start Date 2020-10-22
Est. Completion 2027-03-01
Phase Phase 2

Sponsor

Indiana University

890 total trials

What the Registry Record Tells You About NCT04250259

The ClinicalTrials.gov registry entry for NCT04250259 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 196 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alcoholic Cirrhosis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04250259 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Indiana.

Frequently Asked Questions

What is clinical trial NCT04250259 about?

NCT04250259 is a clinical study titled "SAMe Trial for Patients With Alcoholic Cirrhosis". The proposed of this randomized, double blinded, placebo-controlled study is to assess the effect of SAMe compared to placebo in patients with alcoholic cirrhosis Child Class A and B. The primary objective of the study is to test relationship between SAMe (S-adenosylmethionine) supplement on liver f...

What is the current status of trial NCT04250259?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 196 participants. The study started on 2020-10-22. Estimated completion is 2027-03-01.

What conditions does trial NCT04250259 study?

This clinical trial studies the following conditions: Alcoholic Cirrhosis.

What interventions are being tested in trial NCT04250259?

The interventions under investigation include: Placebo (DRUG), SAMe 400 mg tablet (DRUG).

Who is sponsoring clinical trial NCT04250259?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04250259 being conducted?

This trial has 2 study locations across California, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.