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NCT06617871 · ClinicalTrials.gov registry record · NA
Mechanical Alignment Vs Kalipered Kinematic Alignment Total Knee Arthroplasty
A NA study of Knee Osteoarthritis and Knee Arthropathy, sponsored by Northwestern University.
- Recruiting
- Registry status
- NA
- Development phase
- 95
- Enrollment target
- 1
- Study location
NCT06617871: Recruiting NA study of Knee Osteoarthritis and Knee Arthropathy, sponsored by Northwestern University.
NCT06617871 is a NA study of Knee Osteoarthritis and Knee Arthropathy that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 95 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06617871, a NA study of Knee Osteoarthritis and Knee Arthropathy, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- NA
- Development phase
- 95 participants
- Enrollment target
- 1
- Study location
Study Summary
Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA). The neutral position is different than the human knee's natural position, so MA often requires the surgeon to make additional cuts to the ligaments and other soft tissue around the knee. More recently surgeons have started to place the new joint in a position that more closely replicates the natural alignment of the human knee. This is called Kinemetic Alignment (KA). KA can be done without additional soft tissue dissection but the procedure requires a higher level of precision that can be difficult to achieve in every case. Some studies have found no difference in outcomes between MA and KA, whereas others have found KA to be superior. But these were small studies or studies that did not consider patient-rated outcomes.
Primary Outcome
The Knee Injury and Osteoarthritis Score - Joint Replacement (KOOS-JR) score; range: 0 (worst knee health) - 100 (perfect knee health)
Conditions Studied
Interventions
- PROCEDURE Mechanical Alignment (MA)
- PROCEDURE Kinematic Alignment (KA) Interventions:
Study Locations (1)
Illinois
- Northwestern Medicine - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 95 participants |
| Start Date | 2024-08-01 |
| Est. Completion | 2028-12 |
| Phase | NA |
What NCT06617871 shows while recruiting
NCT06617871 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 95 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (69% lower).
The record links to 2 conditions, with Knee Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Mechanical Alignment (MA) is the first listed.
NCT06617871 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT06617871 about?
NCT06617871 is a clinical study titled "Mechanical Alignment Vs Kalipered Kinematic Alignment Total Knee Arthroplasty". Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA). The neutral position is different than the human knee's natural position, so MA oft...
What is the current status of trial NCT06617871?
This trial is currently recruiting. It is a NA study. The enrollment target is 95 participants. The study started on 2024-08-01. Estimated completion is 2028-12.
What conditions does trial NCT06617871 study?
This clinical trial studies the following conditions: Knee Osteoarthritis, Knee Arthropathy.
What interventions are being tested in trial NCT06617871?
The interventions under investigation include: Mechanical Alignment (MA) (PROCEDURE), Kinematic Alignment (KA) Interventions: (PROCEDURE).
Who is sponsoring clinical trial NCT06617871?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06617871 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06617871's enrollment target sits among peer trials
95 47th of 101 higher than 54 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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