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NCT06617871 · ClinicalTrials.gov registry record · NA

Mechanical Alignment Vs Kalipered Kinematic Alignment Total Knee Arthroplasty

A NA study of Knee Osteoarthritis and Knee Arthropathy, sponsored by Northwestern University.

Recruiting
Registry status
NA
Development phase
95
Enrollment target
1
Study location

NCT06617871 is a NA study of Knee Osteoarthritis and Knee Arthropathy that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 95 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06617871, a NA study of Knee Osteoarthritis and Knee Arthropathy, is actively recruiting participants, sponsored by Northwestern University.

RECRUITING
Registry status
NA
Development phase
95 participants
Enrollment target
1
Study location

Study Summary

Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA). The neutral position is different than the human knee's natural position, so MA often requires the surgeon to make additional cuts to the ligaments and other soft tissue around the knee. More recently surgeons have started to place the new joint in a position that more closely replicates the natural alignment of the human knee. This is called Kinemetic Alignment (KA). KA can be done without additional soft tissue dissection but the procedure requires a higher level of precision that can be difficult to achieve in every case. Some studies have found no difference in outcomes between MA and KA, whereas others have found KA to be superior. But these were small studies or studies that did not consider patient-rated outcomes.

Interventions

  • PROCEDURE Mechanical Alignment (MA)
  • PROCEDURE Kinematic Alignment (KA) Interventions:

Study Locations (1)

Illinois

  • Northwestern Medicine - Chicago

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2024-08-01
Est. Completion 2028-12
Phase NA

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT06617871

The ClinicalTrials.gov registry entry for NCT06617871 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 95 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (69% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Knee Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Mechanical Alignment (MA) is the first listed.

NCT06617871 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT06617871 about?

NCT06617871 is a clinical study titled "Mechanical Alignment Vs Kalipered Kinematic Alignment Total Knee Arthroplasty". Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA). The neutral position is different than the human knee's natural position, so MA oft...

What is the current status of trial NCT06617871?

This trial is currently recruiting. It is a NA study. The enrollment target is 95 participants. The study started on 2024-08-01. Estimated completion is 2028-12.

What conditions does trial NCT06617871 study?

This clinical trial studies the following conditions: Knee Osteoarthritis, Knee Arthropathy.

What interventions are being tested in trial NCT06617871?

The interventions under investigation include: Mechanical Alignment (MA) (PROCEDURE), Kinematic Alignment (KA) Interventions: (PROCEDURE).

Who is sponsoring clinical trial NCT06617871?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06617871 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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