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ClinicalTrials.gov 8 recruiting now full pipeline

Nervous System Diseases: full-pipeline trial registry

8 of 24 indexed Nervous System Diseases trials are currently recruiting.

Corpus placement: #686 of 28,707 conditions by registered trial count.

24 US clinical trials · 8 currently recruiting · #686 of 28,707 conditions by registered trial count

Nervous System Diseases: 24 US clinical trials tracked, 8 recruiting.

Nervous System Diseases is the subject of 24 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Otsuka Pharmaceutical Development & Commercialization, running 3 of these trials.

Enrollment posture brief

Registry condition nervous-system-diseases

OPEN 8 | RECR 33% | LATE 4 | EARLY 3 | RANK #686 | SPON 3

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Aplastic Anemia37.5%Behavior37.5%Nervous System Diseases (thi…33%Allergic Rhinitis8.3%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Nervous System Diseases

Nervous System Diseases lists 8 open slots (33% of 24 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Nervous System Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Nervous System Diseases is recruiting below its size-band peers.

    8 of 24 indexed trials (33.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Nervous System Diseases trials is spread across many organizations.

    Otsuka Pharmaceutical Development & Commercialization accounts for 3 of 24 trials (12.5%). 20 distinct sponsors appear on at least one study for this condition label.

  3. Typical Nervous System Diseases enrolment sits around 90 participants.

    Median target enrolment is 90 among the 24 trials that report a genuine target (sentinel values excluded). 14 of those (58.3%) plan for fewer than 100 participants.

  4. Nervous System Diseases splits between interventional and observational designs.

    16 interventional and 8 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 22Phase 34

Open and recent trials

24 total, page 1 of 1

RECRUITING 3,000 participants

Rett Syndrome Registry

International Rett Syndrome Foundation

NCT05432349

RECRUITING NA 500 participants

Neurologic Stem Cell Treatment Study

MD Stem Cells

NCT02795052

RECRUITING Phase 2 144 participants

Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)

University of Virginia

NCT05565833

RECRUITING 80 participants

SQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism

American Federation of Medical Synergetics

NCT03222375

RECRUITING NA 76 participants

Brain Connections for Arm Movement After Stroke

VA Office of Research and Development

NCT04286516

RECRUITING NA 12 participants

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

Kessler Foundation

NCT05731986

RECRUITING NA 10 participants

Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

Jorge Gonzalez-Martinez

NCT06303869

RECRUITING NA 5 participants

The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

Kessler Foundation

NCT05725499

ACTIVE NOT RECRUITING Phase 3 1,175 participants

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

Eli Lilly and Company

NCT05738486

ACTIVE NOT RECRUITING Phase 3 106 participants

A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

Capricor

NCT05126758

ACTIVE NOT RECRUITING NA 90 participants

Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms

Jonsson Comprehensive Cancer Center

NCT00690196

COMPLETED 450 participants

Safety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previously Participated in a Double-blind Trial of Brexpiprazole or Placebo

Otsuka Pharmaceutical Development & Commercialization

NCT02192554

COMPLETED Phase 3 433 participants

A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of 2 Fixed Doses of Brexpiprazole in the Treatment of Alzheimer's Agitation

Otsuka Pharmaceutical Development & Commercialization

NCT01862640

COMPLETED NA 340 participants

pRESET for Occlusive Stroke Treatment

phenox

NCT03994822

COMPLETED 300 participants

Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001667

COMPLETED Phase 3 270 participants

Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type

Otsuka Pharmaceutical Development & Commercialization

NCT01922258

COMPLETED NA 90 participants

Dietary Supplements for the Treatment of Angelman Syndrome

University of California, San Diego

NCT00348933

COMPLETED NA 80 participants

Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers

Elizabeth K Rhodus

NCT05202223

COMPLETED 62 participants

StimRouter Registry Clinical Protocol

Bioness

NCT03913689

COMPLETED 60 participants

Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity

Vanderbilt University Medical Center

NCT03209960

COMPLETED 60 participants

Using Telemedicine to Improve Spasticity Diagnosis Rates

Vanderbilt University Medical Center

NCT03211390

COMPLETED 48 participants

Humoral and T-Cell Responses to COVID-19 Vaccination in Multiple Sclerosis Patients Treated With Ocrelizumab Treated With Ocrelizumab or Natalizumab

Dragonfly Research

NCT04837651

COMPLETED Phase 2 37 participants

Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients

Avidity Biosciences

NCT05479981

COMPLETED Phase 1 19 participants

Study of Pioglitazone in Sporadic Inclusion Body Myositis

Johns Hopkins University

NCT03440034

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 3 4

Named interventions

Most-linked intervention names on Nervous System Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Brexpiprazole, OPC-34712 Drug
2 trials
Placebo Drug
2 trials
Harmony at HOME (H@H) Behavioral
1 trials
T-Detect COVID T-cell blood test Device
1 trials
Elecsys semi-quantitative Anti-SARS-CoV-2 antibody test Device
1 trials
AOC 1001 Drug
1 trials
Teleneurological Examination Diagnostic test
1 trials
Neurological Examination Diagnostic test
1 trials

US sites by state

Facility locations filed on Nervous System Diseases trials. A trial with sites in several states counts in each.

California 11 trials
Massachusetts 7 trials
Florida 7 trials
Pennsylvania 5 trials
Virginia 4 trials
Texas 4 trials
Ohio 4 trials
New York 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Nervous System Diseases page

24 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Nervous System Diseases condition card totals 24 registered trials; most-linked intervention Brexpiprazole, OPC-34712; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.