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NCT05439655 · ClinicalTrials.gov registry record · NA
Acute Recording of Stereotyped High-Frequency Oscillations
A NA study of Epilepsy, sponsored by Mayo Clinic.
- Active
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 2
- Study locations
NCT05439655: Active NA study of Epilepsy, sponsored by Mayo Clinic.
NCT05439655 is a NA study of Epilepsy that is active but no longer recruiting, run by Mayo Clinic. The registered enrollment target is 12 participants, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05439655, a NA study of Epilepsy, is active but no longer recruiting, sponsored by Mayo Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 2
- Study locations
Study Summary
Overall, this study will investigate the functional utility of stereotyped HFOs by capturing them with a new implantable system (Brain Interchange - BIC of CorTec), which can sample neural data at higher rates \>=1kHz and deliver targeted electrical stimulation to achieve seizure control. In contrast to current closed-loop systems (RNS), which wait for the seizure to start before delivering stimulation, the BIC system will monitor the spatial topography and rate of stereotyped HFOs and deliver targeted stimulation to these HFO generating areas to prevent seizures from occurring. If the outcomes of our research in an acute setting become successful, the investigators will execute a clinical trial and run the developed methods with the implantable BIC system in a chronic ambulatory setting.
Primary Outcome
Outcome-1 will quantify the feasibility of robust data recording and transmission with the BIC system in the epilepsy monitoring unit (EMU). The investigators will develop software tools to communicate with the BIC directly from MATLAB and Simulink. The incoming data from the implantable system will be visualized with gHIsys, the high-speed data processing libraries of gTec. At the end of the first year, in the epilepsy monitoring unit (EMU), the investigators will test the feasibility of recodi
Conditions Studied
Interventions
- DEVICE Brain Interchange System
Study Locations (2)
Minnesota
- Mayo Clinic - Rochester
Texas
- Baylor College of Medicine - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2027-03-31 |
| Phase | NA |
What the registry record for NCT05439655 still lists
NCT05439655 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Epilepsy appearing as the primary indexed condition, and to 1 intervention - of which Brain Interchange System is the first listed.
NCT05439655 reports a single indexed study location in Minnesota, Texas.
Frequently Asked Questions
What is clinical trial NCT05439655 about?
NCT05439655 is a clinical study titled "Acute Recording of Stereotyped High-Frequency Oscillations". Overall, this study will investigate the functional utility of stereotyped HFOs by capturing them with a new implantable system (Brain Interchange - BIC of CorTec), which can sample neural data at higher rates \>=1kHz and deliver targeted electrical stimulation to achieve seizure control. In contras...
What is the current status of trial NCT05439655?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2021-09-01. Estimated completion is 2027-03-31.
What conditions does trial NCT05439655 study?
This clinical trial studies the following conditions: Epilepsy.
What interventions are being tested in trial NCT05439655?
The interventions under investigation include: Brain Interchange System (DEVICE).
Who is sponsoring clinical trial NCT05439655?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05439655 being conducted?
This trial has 2 study locations across Minnesota, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Epilepsy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05439655's enrollment target sits among peer trials
12 144th of 160 higher than 16 of 160 other Epilepsy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Epilepsy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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