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NCT05380531 · ClinicalTrials.gov registry record · NA
Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section
A NA study of Opioid Use and Cesarean Section Complications, sponsored by Senthil Sadhasivam.
- Recruiting
- Registry status
- NA
- Development phase
- 600
- Enrollment target
- 2
- Study locations
NCT05380531: Recruiting NA study of Opioid Use and Cesarean Section Complications, sponsored by Senthil Sadhasivam.
NCT05380531 is a NA study of Opioid Use and Cesarean Section Complications that is actively recruiting participants, run by Senthil Sadhasivam. The registered enrollment target is 600 participants, below the 148,254-participant average among 105 other Opioid Use trials with a reported enrollment target (100% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05380531, a NA study of Opioid Use and Cesarean Section Complications, is actively recruiting participants, sponsored by Senthil Sadhasivam.
- RECRUITING
- Registry status
- NA
- Development phase
- 600 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this collaborative CTSA (Clinical and Translational Science Award) application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in breastfeeding mothers and their infants
Primary Outcome
The investigators will look at specific CYP2D6, ABCB1, FAAH, OPRM1, and COMT variants to find correlations with patients who experience RD and PONV in the immediate post-surgical period (4 days) in the hospital
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Preoperative Genotyping
Study Locations (2)
Pennsylvania
- UPMC Magee Women's Hospital - Pittsburgh
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2022-12-05 |
| Est. Completion | 2026-10-30 |
| Phase | NA |
What NCT05380531 shows while recruiting
NCT05380531 is an interventional study that assigns participants to a tested intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 148,254-participant average among 105 other Opioid Use trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Opioid Use appearing as the primary indexed condition, and to 1 intervention - of which Preoperative Genotyping is the first listed.
NCT05380531 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05380531 about?
NCT05380531 is a clinical study titled "Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section". The purpose of this collaborative CTSA (Clinical and Translational Science Award) application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in breastfeeding mothe...
What is the current status of trial NCT05380531?
This trial is currently recruiting. It is a NA study. The enrollment target is 600 participants. The study started on 2022-12-05. Estimated completion is 2026-10-30.
What conditions does trial NCT05380531 study?
This clinical trial studies the following conditions: Opioid Use, Cesarean Section Complications.
What interventions are being tested in trial NCT05380531?
The interventions under investigation include: Preoperative Genotyping (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05380531?
This trial is sponsored by Senthil Sadhasivam, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05380531 being conducted?
This trial has 2 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05380531's enrollment target sits among peer trials
600 14th of 105 higher than 91 of 105 other Opioid Use trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Opioid Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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