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NCT06420336 · ClinicalTrials.gov registry record · NA
QL vs LAI for Palatoplasty
A NA study of Postoperative Pain and Opioid Use, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT06420336: Recruiting NA study of Postoperative Pain and Opioid Use, sponsored by Medical University of South Carolina.
NCT06420336 is a NA study of Postoperative Pain and Opioid Use that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 46 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06420336, a NA study of Postoperative Pain and Opioid Use, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will consist of patients ages 6-18 who are undergoing a surgery on the hard or soft palate of the mouth (palatoplasty), with removal of bone from the front of the hip (anterior iliac bone graft harvesting). The patients will be randomized to receive either a unilateral QL block by an anesthesiologist, or local anesthetic infiltration at the surgical incision by the surgeon. The primary aim will be assessing post-operative pain in the first 48 hours after surgery. Secondary outcomes will include pain medication use in the first 48 hours after surgery, block resolution time, and evaluating any complications associated with the QL block or local anesthetic infiltration.
Primary Outcome
Using the Wong-Baker FACES Pain Rating Scale, patients will report their average pain from 0 hours post-op through 48-hours post-op at various intervals. In the Post-Anesthesia Recovery Unit, pain scores will be evaluated every 15 minutes as clinically able, until discharged from the PACU. On Post-Op Day 1 at 9:00 am, pains average pain score from discharge to PACU to midnight will be reported. At approximately 24-hours after surgery ends, pain scores from midnight to 23-hours post-op will be re
Conditions Studied
Interventions
- PROCEDURE Quadratus lumborum block
- PROCEDURE Local anesthetic infiltration
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2024-06-25 |
| Est. Completion | 2026-07-30 |
| Phase | NA |
What NCT06420336 shows while recruiting
NCT06420336 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (80% lower).
The record links to 3 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Quadratus lumborum block is the first listed.
NCT06420336 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT06420336 about?
NCT06420336 is a clinical study titled "QL vs LAI for Palatoplasty". This study will consist of patients ages 6-18 who are undergoing a surgery on the hard or soft palate of the mouth (palatoplasty), with removal of bone from the front of the hip (anterior iliac bone graft harvesting). The patients will be randomized to receive either a unilateral QL block by an anes...
What is the current status of trial NCT06420336?
This trial is currently recruiting. It is a NA study. The enrollment target is 46 participants. The study started on 2024-06-25. Estimated completion is 2026-07-30.
What conditions does trial NCT06420336 study?
This clinical trial studies the following conditions: Postoperative Pain, Opioid Use, Cleft Palate.
What interventions are being tested in trial NCT06420336?
The interventions under investigation include: Quadratus lumborum block (PROCEDURE), Local anesthetic infiltration (PROCEDURE).
Who is sponsoring clinical trial NCT06420336?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06420336 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06420336's enrollment target sits among peer trials
46 105th of 120 higher than 16 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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