Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05331599 · ClinicalTrials.gov registry record

Recurrence Markers, Cognitive Burden and Neurobiological Homeostasis in Late-Life Depression

A clinical trial of Cognitive Dysfunction and Recurrence, sponsored by University of Illinois at Chicago.

Active
Registry status
210
Enrollment target
1
Study location

NCT05331599 is a study of Cognitive Dysfunction and Recurrence that is active but no longer recruiting, run by University of Illinois at Chicago. The registered enrollment target is 210 participants, below the 1,988-participant average among 45 other Cognitive Dysfunction trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05331599, a study of Cognitive Dysfunction and Recurrence, is active but no longer recruiting, sponsored by University of Illinois at Chicago.

ACTIVE NOT RECRUITING
Registry status
210 participants
Enrollment target
1
Study location

Study Summary

Late-life depression (LLD) is associated with disability, increased risk for cognitive decline and dementia, elevated suicide risk, and greater all-cause mortality. These outcomes are related to depression being a recurrent disorder, with repeated episodes over a patient's lifetime. Recurrence rates (defined as including both relapse and recurrence) are high in LLD. The goals of this study are to identify neurobiological factors that predict recurrence risk, and examine how cognitive performance changes are both influenced by these neurobiological factors and also predict recurrence risk.

Study Locations (1)

Illinois

  • University of Illinois at Chicago - Chicago

Trial Details

FieldValue
Enrollment Target 210 participants
Start Date 2020-06-01
Est. Completion 2026-01-15

Sponsor

University of Illinois at Chicago

430 total trials

What the Registry Record Tells You About NCT05331599

The ClinicalTrials.gov registry entry for NCT05331599 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 210 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,988-participant average among 45 other Cognitive Dysfunction trials with a reported enrollment target (89% lower). The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Cognitive Dysfunction appearing as the primary indexed condition, and to 0 interventions.

NCT05331599 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT05331599 about?

NCT05331599 is a clinical study titled "Recurrence Markers, Cognitive Burden and Neurobiological Homeostasis in Late-Life Depression". Late-life depression (LLD) is associated with disability, increased risk for cognitive decline and dementia, elevated suicide risk, and greater all-cause mortality. These outcomes are related to depression being a recurrent disorder, with repeated episodes over a patient's lifetime. Recurrence rates...

What is the current status of trial NCT05331599?

This trial is currently active not recruiting. The enrollment target is 210 participants. The study started on 2020-06-01. Estimated completion is 2026-01-15.

What conditions does trial NCT05331599 study?

This clinical trial studies the following conditions: Cognitive Dysfunction, Recurrence, Depression in Old Age.

Who is sponsoring clinical trial NCT05331599?

This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05331599 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cognitive Dysfunction

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.