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NCT05965518 · ClinicalTrials.gov registry record · NA
High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV
A NA study of HIV and Cognitive Dysfunction, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05965518: Recruiting NA study of HIV and Cognitive Dysfunction, sponsored by University of Alabama at Birmingham.
NCT05965518 is a NA study of HIV and Cognitive Dysfunction that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 60 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05965518, a NA study of HIV and Cognitive Dysfunction, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition. The overall goals of this proposal are to determine whether 16 weeks of structured high-intensity interval training (HIIT) can overcome vascular and cognitive impairments (Aim 1) to a greater extent than continuous moderate exercise. Additionally, investigator will seek to identify barriers to engagement in exercise and the participants' perceptions of the study and exercise interventions (Aim 2). This study will enroll 60 participants in Birmingham, Alabama. Data collection will occur at each visit, with baseline data collected at the initial visit with a 3-month follow-up occurring following completion of the intervention.
Primary Outcome
Arterial stiffness is a continuous measure of cardiovascular disease risk.
Conditions Studied
Interventions
- BEHAVIORAL High-Intensity Interval Training
- BEHAVIORAL Continuous Moderate Exercise
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-02-05 |
| Est. Completion | 2028-12 |
| Phase | NA |
What NCT05965518 shows while recruiting
NCT05965518 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 440-participant average among 303 other HIV trials with a reported enrollment target (86% lower).
The record links to 3 conditions, with HIV appearing as the primary indexed condition, and to 2 interventions - of which High-Intensity Interval Training is the first listed.
NCT05965518 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT05965518 about?
NCT05965518 is a clinical study titled "High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV". This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition. The overall goals of this proposal are to determine whether 16 weeks of structured high-intensity interval training (HIIT) can overcome vascular and cogniti...
What is the current status of trial NCT05965518?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-02-05. Estimated completion is 2028-12.
What conditions does trial NCT05965518 study?
This clinical trial studies the following conditions: HIV, Cognitive Dysfunction, Arterial Stiffness.
What interventions are being tested in trial NCT05965518?
The interventions under investigation include: High-Intensity Interval Training (BEHAVIORAL), Continuous Moderate Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT05965518?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05965518 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for HIV
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05965518's enrollment target sits among peer trials
60 200th of 303 higher than 100 of 303 other HIV trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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