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NCT04558164 · ClinicalTrials.gov registry record · NA
Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment
A NA study of Cognitive Dysfunction and Memory Disorders in Old Age, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT04558164: Recruiting NA study of Cognitive Dysfunction and Memory Disorders in Old Age, sponsored by University of California, Los Angeles.
NCT04558164 is a NA study of Cognitive Dysfunction and Memory Disorders in Old Age that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 70 participants, below the 1,991-participant average among 45 other Cognitive Dysfunction trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04558164, a NA study of Cognitive Dysfunction and Memory Disorders in Old Age, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to see if stimulation of the brain can improve memory. The investigators will use a device called transcranial magnetic stimulation that can stimulate and activate a specific part of the brain that is important for memory. The study will enroll MCI subjects and subjects with subjective memory complaints who will be randomly assigned to receive active or sham brain stimulation. 'Blinded' or 'sham-controlled' means that the subject will not know whether the treatment they receive is the active treatment or the non-active stimulation. In the 'sham' condition, the stimulator will turn on but will not actually be stimulating the target brain region.
Primary Outcome
Verbal memory will be measured using a free recall task where participants learn a list of everyday words and are asked to recall as many words as they can remember after a period of distraction. Proportion of recollected words will be used to quantify memory performance changes.
Conditions Studied
Interventions
- DEVICE Active Theta Burst Stimulation
- DEVICE Sham Theta Burst Stimulation
Study Locations (1)
California
- University of California Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2021-01-26 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT04558164 shows while recruiting
NCT04558164 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 1,991-participant average among 45 other Cognitive Dysfunction trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Cognitive Dysfunction appearing as the primary indexed condition, and to 2 interventions - of which Active Theta Burst Stimulation is the first listed.
NCT04558164 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04558164 about?
NCT04558164 is a clinical study titled "Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment". The purpose of this study is to see if stimulation of the brain can improve memory. The investigators will use a device called transcranial magnetic stimulation that can stimulate and activate a specific part of the brain that is important for memory. The study will enroll MCI subjects and subjects ...
What is the current status of trial NCT04558164?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2021-01-26. Estimated completion is 2026-06-30.
What conditions does trial NCT04558164 study?
This clinical trial studies the following conditions: Cognitive Dysfunction, Memory Disorders in Old Age.
What interventions are being tested in trial NCT04558164?
The interventions under investigation include: Active Theta Burst Stimulation (DEVICE), Sham Theta Burst Stimulation (DEVICE).
Who is sponsoring clinical trial NCT04558164?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04558164 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cognitive Dysfunction
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04558164's enrollment target sits among peer trials
70 24th of 45 higher than 22 of 45 other Cognitive Dysfunction trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cognitive Dysfunction trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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