Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
NCT05287126 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years up to \< 18 years of age). Participants who will complete the total 52-week treatment period will have the opportunity to continue in a Long-Term Extension (LTE) Period of up to 4 years (5 years after study enrollment).
Conditions Studied
Interventions
- DRUG Etrasimod
Study Locations (20)
California
- Valley View Wellness Medical Center — Garden Grove
- Loma Linda Children's Hospital — Loma Linda
- Loma Linda University Clinical Trial Center — Loma Linda
- Loma Linda University Eye Institute — Loma Linda
- Loma Linda University Medical Center — Loma Linda
- Loma Linda University Pediatric Clinics — Loma Linda
- Loma Linda University Children's Hospital Pediatric Specialty Clinics — San Bernardino
- University of California San Francisco, — San Francisco
- University of California San Francisco — San Francisco
- University of California,San Francisco Pediatric ClinicalResearch Center (PCRC) — San Francisco
Arkansas
- Arkansas Children's (IP Address) — Little Rock
- Arkansas Children's — Little Rock
Michigan
- William Beaumont Hospitals Reference Laboratory — Royal Oak
- William Beaumont Hospital — Royal Oak
Ohio
- University Hospitals Cleveland Medical Center Rainbow Babies & Children's Hospital — Cleveland
- University Hospitals Cleveland Medical Center — Cleveland
Florida
- Arnold Palmer Hospital - Center for Digestive Health and Nutrition — Orlando
Illinois
- University of Chicago Medical Center — Chicago
Massachusetts
- Boston Children's Hospital — Boston
Texas
- Advance Clinical Trial PLLC — Abilene
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2022-12-16 |
| Est. Completion | 2031-08-07 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05287126
The ClinicalTrials.gov registry entry for NCT05287126 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 769 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Ulcerative Colitis appearing as the primary indexed condition, and to 1 intervention — of which Etrasimod is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05287126 reports 20 study locations spanning 8 distinct geographic areas — top geographies include California, Arkansas, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05287126 about?
NCT05287126 is a clinical study titled "A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis". The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years up to \< 18 years of age). Participants who will complete the total 52-week treatment period will ha...
What is the current status of trial NCT05287126?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2022-12-16. Estimated completion is 2031-08-07.
What conditions does trial NCT05287126 study?
This clinical trial studies the following conditions: Ulcerative Colitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05287126?
The interventions under investigation include: Etrasimod (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05287126?
This trial is sponsored by Pfizer, which has 769 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05287126 being conducted?
This trial has 20 study locations across Arkansas, California, Florida, Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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