Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 2

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

NCT06254950 · View on ClinicalTrials.gov ↗

Study Summary

The main aim of this study is to learn if TAK-279 reduces bowel inflammation and symptoms compared to placebo. Another aim is to compare any medical problems that participants have when they take TAK-279 or placebo and how well the participants tolerate any problems. The participants will take capsules of either TAK-279 or placebo for up to 3 months (12 weeks). Then all the participants will receive TAK-279 for the rest of the treatment part of the study (1 year or 52 weeks). During the study, participants will visit their study clinic several times.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG TAK-279

Study Locations (20)

Florida

  • West Central Gastroenterology, LLP, d/b/a/ Gastro Florida — Clearwater
  • Auzmer Research — Lakeland
  • GI PROS, Inc. — Naples
  • USF Health Morsani Center for Advanced Healthcare — Tampa

California

  • GastroIntestinal BioSciences — Los Angeles
  • United Medical Doctors — Murrieta

Georgia

  • Emory University Hospital, The Emory Clinic — Atlanta
  • Atlanta Center For Gastroenterology, P.C. — Decatur

Texas

  • Novel Research, LLC — Bellaire
  • Tyler Research Institute, LLC — Tyler

South Australia

  • Flinders Medical Centre — Bedford Park
  • The Queen Elizabeth Hospital — Woodville

Kentucky

  • University Of Louisville — Louisville

Maryland

  • Woodholme Gastroenterology Associates — Glen Burnie

Nevada

  • Las Vegas Medical Research — Las Vegas

Trial Details

FieldValue
Enrollment Target 207 participants
Start Date 2024-03-29
Est. Completion 2027-08-04
Phase Phase 2

Sponsor

Takeda

387 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06254950

The ClinicalTrials.gov registry entry for NCT06254950 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 207 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Takeda, which has 387 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Ulcerative Colitis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06254950 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Florida, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06254950 about?

NCT06254950 is a clinical study titled "A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis". The main aim of this study is to learn if TAK-279 reduces bowel inflammation and symptoms compared to placebo. Another aim is to compare any medical problems that participants have when they take TAK-279 or placebo and how well the participants tolerate any problems. The participants will take caps...

What is the current status of trial NCT06254950?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 207 participants. The study started on 2024-03-29. Estimated completion is 2027-08-04.

What conditions does trial NCT06254950 study?

This clinical trial studies the following conditions: Ulcerative Colitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06254950?

The interventions under investigation include: Placebo (DRUG), TAK-279 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06254950?

This trial is sponsored by Takeda, which has 387 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06254950 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Kentucky, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial