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NCT04998877 · ClinicalTrials.gov registry record
Physical Activity, Cardiac and Skeletal Muscle Energetics in Healthy Subjects and HFpEF Patients
A clinical trial of Heart Failure With Preserved Ejection Fraction, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- 60
- Enrollment target
- 1
- Study location
NCT04998877: Recruiting study of Heart Failure With Preserved Ejection Fraction, sponsored by Johns Hopkins University.
NCT04998877 is a study of Heart Failure With Preserved Ejection Fraction that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 60 participants, below the 2,287-participant average among 42 other Heart Failure With Preserved Ejection Fraction trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04998877, a study of Heart Failure With Preserved Ejection Fraction, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This research is being done to better understand the relationship between information collected by wearable devices and clinical measurements in people with heart failure with preserved ejection fraction (HFpEF) and others without HFpEF. This is an observational study with no study intervention or randomization. Participants will undergo baseline history and physical, 12-lead EKG, laboratory studies of blood/serum/urine, echocardiography, activity questionnaire, 6 minute walk test, and placement of wearable devices to be worn for up to 14 days (activity monitors, EKG monitor and continuous glucose monitor). Participants will return after \~14 days of wearing the devices and repeat of physical examination, 12-lead EKG, 6 minute walk test, activity questionnaire. Additionally, participants will undergo magnetic resonance imaging (MRI) of their leg with exercise, cardiopulmonary exercise testing (CPET) and, for those who qualify, magnetic resonance imaging (MRI) of their heart with exercise.
Primary Outcome
Moderate to Vigorous Physical Activity (MVPA; minutes per day); Non-sedentary activity (i.e. sum of light activity and MVPA minutes per day.
Conditions Studied
Study Locations (1)
Maryland
- Johns Hopkins Hosptial - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-08-04 |
| Est. Completion | 2026-07-01 |
What NCT04998877 shows while recruiting
NCT04998877 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 2,287-participant average among 42 other Heart Failure With Preserved Ejection Fraction trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Heart Failure With Preserved Ejection Fraction appearing as the primary indexed condition, and to 0 interventions.
NCT04998877 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04998877 about?
NCT04998877 is a clinical study titled "Physical Activity, Cardiac and Skeletal Muscle Energetics in Healthy Subjects and HFpEF Patients". This research is being done to better understand the relationship between information collected by wearable devices and clinical measurements in people with heart failure with preserved ejection fraction (HFpEF) and others without HFpEF. This is an observational study with no study intervention or r...
What is the current status of trial NCT04998877?
This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2021-08-04. Estimated completion is 2026-07-01.
What conditions does trial NCT04998877 study?
This clinical trial studies the following conditions: Heart Failure With Preserved Ejection Fraction.
Who is sponsoring clinical trial NCT04998877?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04998877 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure With Preserved Ejection Fraction
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04998877's enrollment target sits among peer trials
60 24th of 42 higher than 18 of 42 other Heart Failure With Preserved Ejection Fraction trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure With Preserved Ejection Fraction trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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