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NCT04984811 · ClinicalTrials.gov registry record · Phase 2
NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLC
A Phase 2 study of Non-Small Cell Lung Cancer and Carcinoma, Non-Small Cell Lung, sponsored by NeoImmuneTech.
- Active
- Registry status
- Phase 2
- Development phase
- 83
- Enrollment target
- 20
- Study locations
NCT04984811 is a Phase 2 study of Non-Small Cell Lung Cancer and Carcinoma, Non-Small Cell Lung that is active but no longer recruiting, run by NeoImmuneTech. The registered enrollment target is 83 participants, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (87% lower). The trial reports 20 study locations across 14 states.
The verdict
NCT04984811, a Phase 2 study of Non-Small Cell Lung Cancer and Carcinoma, Non-Small Cell Lung, is active but no longer recruiting, sponsored by NeoImmuneTech.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 83 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a multicenter, open-label, single-arm Phase II study to evaluate anti-tumor efficacy and safety of NT-I7 in combination with atezolizumab in subjects with PD-L1-expressing (TPS ≥ 1%), metastatic (Stage IV) or locally advanced squamous or non-squamous NSCLC who have not received prior systemic therapy in the metastatic or locally advanced setting. Eligible subjects must have measurable disease according to RECIST 1.1. This Phase II study will enroll up to 83 subjects.
Conditions Studied
Interventions
- DRUG Atezolizumab
- DRUG efineptakin alfa
Study Locations (20)
Florida
- Florida Cancer Specialists - South Research Office - Fort Myers
- BRCR Medical Center - Plantation
- Florida Cancer Specialists - North Research Office - St. Petersburg
- Florida Cancer Specialists - East Research Office - West Palm Beach
Tennessee
- Tennessee Oncology - Chattanooga - Chattanooga
- Thompson Cancer Survival Center - Knoxville
- Tennessee Oncology - Nashville - Nashville
Kentucky
- Norton Cancer Institute - Louisville
- Pikeville Medical Center, Inc. - Pikeville
Alabama
- University of South Alabama - Mobile
California
- TOI Clinical Research - Cerritos
Connecticut
- Eastern CT Hematology & Oncology Associates - Norwich
Georgia
- University Cancer and Blood Center - Athens
Indiana
- Goshen Center for Cancer Care - Goshen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 83 participants |
| Start Date | 2021-11-03 |
| Est. Completion | 2025-03 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04984811
The ClinicalTrials.gov registry entry for NCT04984811 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 83 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (87% lower). The listed sponsor is NeoImmuneTech, which has 6 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which Atezolizumab is the first listed.
NCT04984811 reports 20 study locations spanning 14 distinct geographic areas - top geographies include Florida, Tennessee, Kentucky.
Frequently Asked Questions
What is clinical trial NCT04984811 about?
NCT04984811 is a clinical study titled "NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLC". This is a multicenter, open-label, single-arm Phase II study to evaluate anti-tumor efficacy and safety of NT-I7 in combination with atezolizumab in subjects with PD-L1-expressing (TPS ≥ 1%), metastatic (Stage IV) or locally advanced squamous or non-squamous NSCLC who have not received prior systemi...
What is the current status of trial NCT04984811?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 83 participants. The study started on 2021-11-03. Estimated completion is 2025-03.
What conditions does trial NCT04984811 study?
This clinical trial studies the following conditions: Non-Small Cell Lung Cancer, Carcinoma, Non-Small Cell Lung, Non-Small-Cell Lung Carcinoma, Nonsmall Cell Lung Cancer.
What interventions are being tested in trial NCT04984811?
The interventions under investigation include: Atezolizumab (DRUG), efineptakin alfa (DRUG).
Who is sponsoring clinical trial NCT04984811?
This trial is sponsored by NeoImmuneTech, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04984811 being conducted?
This trial has 20 study locations across Alabama, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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