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NCT04626674 · ClinicalTrials.gov registry record · Phase 1

A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)

A Phase 1 study of Muscular Dystrophy, Duchenne, sponsored by Sarepta Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
83
Enrollment target
5
Study locations

NCT04626674 is a Phase 1 study of Muscular Dystrophy, Duchenne that is actively recruiting participants, run by Sarepta Therapeutics. The registered enrollment target is 83 participants, roughly in line with the 87-participant average among 4 other Muscular Dystrophy, Duchenne trials with a reported enrollment target. The trial reports 5 study locations across 4 states.

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The verdict

NCT04626674, a Phase 1 study of Muscular Dystrophy, Duchenne, is actively recruiting participants, sponsored by Sarepta Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
83 participants
Enrollment target
5
Study locations

Study Summary

This is an open-label gene transfer therapy study evaluating the safety of and expression from delandistrogene moxeparvovec in participants with DMD. The maximum participant duration for this study is 156 weeks.

Interventions

  • GENETIC delandistrogene moxeparvovec

Study Locations (5)

California

  • Stanford University - Palo Alto
  • University of California, Davis - Sacramento

Missouri

  • Washington University in St. Louis - St Louis

Ohio

  • Nationwide Children's Hospital - Columbus

Virginia

  • Children's Hospital of The King's Daughters - Norfolk

Trial Details

FieldValue
Enrollment Target 83 participants
Start Date 2020-11-23
Est. Completion 2028-02-29
Phase Phase 1

Sponsor

Sarepta Therapeutics

33 total trials

What the Registry Record Tells You About NCT04626674

The ClinicalTrials.gov registry entry for NCT04626674 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 83 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 87-participant average among 4 other Muscular Dystrophy, Duchenne trials with a reported enrollment target. The listed sponsor is Sarepta Therapeutics, which has 33 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Muscular Dystrophy, Duchenne appearing as the primary indexed condition, and to 1 intervention - of which delandistrogene moxeparvovec is the first listed.

NCT04626674 reports 5 study locations spanning 4 distinct geographic areas - top geographies include California, Missouri, Ohio.

Frequently Asked Questions

What is clinical trial NCT04626674 about?

NCT04626674 is a clinical study titled "A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)". This is an open-label gene transfer therapy study evaluating the safety of and expression from delandistrogene moxeparvovec in participants with DMD. The maximum participant duration for this study is 156 weeks.

What is the current status of trial NCT04626674?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 83 participants. The study started on 2020-11-23. Estimated completion is 2028-02-29.

What conditions does trial NCT04626674 study?

This clinical trial studies the following conditions: Muscular Dystrophy, Duchenne.

What interventions are being tested in trial NCT04626674?

The interventions under investigation include: delandistrogene moxeparvovec (GENETIC).

Who is sponsoring clinical trial NCT04626674?

This trial is sponsored by Sarepta Therapeutics, which has 33 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04626674 being conducted?

This trial has 5 study locations across California, Missouri, Ohio, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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