Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

Study Evaluating Intravitreal hI-con1™ in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration

NCT02358889 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the safety, biological activity and pharmacodynamic effect of repeated intravitreal doses of hI-con1 0.3 mg administered as monotherapy and in combination with ranibizumab 0.5 mg compared to ranibizumab 0.5 mg monotherapy in treating patients with choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD).

Interventions

  • OTHER Sham injection
  • BIOLOGICAL hI-con1
  • BIOLOGICAL ranibizumab

Study Locations (20)

California

  • — Arcadia
  • — Beverly Hills
  • — Campbell
  • — Glendale
  • — Laguna Hills
  • — Mountain View
  • — Palm Desert
  • — Palo Alto
  • — San Francisco
  • — Santa Ana

Florida

  • — Boynton Beach
  • — Fort Myers
  • — Panama City
  • — Sarasota
  • — Stuart
  • — Winter Haven

Arizona

  • — Phoenix
  • — Phoenix

Colorado

  • — Golden

Georgia

  • — Augusta

Trial Details

FieldValue
Enrollment Target 88 participants
Start Date 2015-02
Est. Completion 2016-09
Phase Phase 2

Sponsor

Iconic Therapeutics

3 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02358889

The ClinicalTrials.gov registry entry for NCT02358889 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Iconic Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Age-related Macular Degeneration appearing as the primary indexed condition, and to 3 interventions — of which Sham injection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02358889 reports 20 study locations spanning 5 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02358889 about?

NCT02358889 is a clinical study titled "Study Evaluating Intravitreal hI-con1™ in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration". The purpose of this study is to evaluate the safety, biological activity and pharmacodynamic effect of repeated intravitreal doses of hI-con1 0.3 mg administered as monotherapy and in combination with ranibizumab 0.5 mg compared to ranibizumab 0.5 mg monotherapy in treating patients with choroidal n...

What is the current status of trial NCT02358889?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 88 participants. The study started on 2015-02. Estimated completion is 2016-09.

What conditions does trial NCT02358889 study?

This clinical trial studies the following conditions: Age-related Macular Degeneration, Choroidal Neovascularization. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02358889?

The interventions under investigation include: Sham injection (OTHER), hI-con1 (BIOLOGICAL), ranibizumab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02358889?

This trial is sponsored by Iconic Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02358889 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial