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NCT04694300 · ClinicalTrials.gov registry record · Phase 4

OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients

A Phase 4 study of Pain, Acute and Osseointegrated Dental Implantation, sponsored by Hersh, Elliot V., DMD, MS, PhD.

Completed
Registry status
Phase 4
Development phase
30
Enrollment target
1
Study location

NCT04694300 is a Phase 4 study of Pain, Acute and Osseointegrated Dental Implantation that has completed, run by Hersh, Elliot V., DMD, MS, PhD. The registered enrollment target is 30 participants, below the 101-participant average among 31 other Pain, Acute trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04694300, a Phase 4 study of Pain, Acute and Osseointegrated Dental Implantation, has completed, sponsored by Hersh, Elliot V., DMD, MS, PhD.

COMPLETED
Registry status
Phase 4
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This double-blind pilot study will evaluate the anti-inflammatory and analgesic effects of an over-the-counter (OTC) regimen of naproxen sodium versus acetaminophen in patients receiving one or two (adjacent) dental implants. It will also confirm that naproxen sodium in the OTC dosage range is a good alternative to immediate-release opioid formulations, which are subject to misuse, abuse and diversion in this patient population.

Conditions Studied

Pain, Acute Osseointegrated Dental Implantation

Interventions

  • DRUG Acetaminophen
  • DRUG Naproxen
  • DRUG Tramadol

Study Locations (1)

Pennsylvania

  • University of Pennsylvania School of Dental Medicine - Philadelphia

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2021-02-07
Est. Completion 2022-08-28
Phase Phase 4

Sponsor

Hersh, Elliot V., DMD, MS, PhD

2 total trials

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What the Registry Record Tells You About NCT04694300

The ClinicalTrials.gov registry entry for NCT04694300 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 101-participant average among 31 other Pain, Acute trials with a reported enrollment target (70% lower). The listed sponsor is Hersh, Elliot V., DMD, MS, PhD, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Pain, Acute appearing as the primary indexed condition, and to 3 interventions - of which Acetaminophen is the first listed.

NCT04694300 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04694300 about?

NCT04694300 is a clinical study titled "OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients". This double-blind pilot study will evaluate the anti-inflammatory and analgesic effects of an over-the-counter (OTC) regimen of naproxen sodium versus acetaminophen in patients receiving one or two (adjacent) dental implants. It will also confirm that naproxen sodium in the OTC dosage range is a goo...

What is the current status of trial NCT04694300?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2021-02-07. Estimated completion is 2022-08-28.

What conditions does trial NCT04694300 study?

This clinical trial studies the following conditions: Pain, Acute, Osseointegrated Dental Implantation.

What interventions are being tested in trial NCT04694300?

The interventions under investigation include: Acetaminophen (DRUG), Naproxen (DRUG), Tramadol (DRUG).

Who is sponsoring clinical trial NCT04694300?

This trial is sponsored by Hersh, Elliot V., DMD, MS, PhD, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04694300 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.