Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
NCT04634552 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the efficacy and safety of talquetamab in participants with relapsed or refractory multiple myeloma at the recommended Phase 2 dose(s) (RP2Ds) (Part 3).
Conditions Studied
Interventions
- DRUG Talquetamab
Study Locations (20)
Other
- UZ Antwerpen — Edegem
- UZ Leuven — Leuven
- CHU de Liège - Domaine Universitaire du Sart Tilman — Liège
- UCL - Saint Luc — Woluwe-Saint-Lambert
- Peking University Third Hospital — Beijing
- Sun Yat Sen University Cancer Center — Guangzhou
New York
- NYU Langone Health — New York
- Mount Sinai Medical Center — New York
- University of Rochester Medical Center — Rochester
Alabama
- University of Alabama Birmingham — Birmingham
Arkansas
- University of Arkansas for Medical Sciences — Little Rock
California
- City of Hope — Duarte
Florida
- Memorial Healthcare System — Hollywood
Georgia
- Emory University Winship Cancer Institute — Atlanta
Illinois
- University of Chicago — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 510 participants |
| Start Date | 2021-02-01 |
| Est. Completion | 2029-03-30 |
| Phase | Phase 2 |
Interested in This Trial?
Always speak with your doctor before enrolling in a clinical trial.
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04634552
The ClinicalTrials.gov registry entry for NCT04634552 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 510 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 442 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Hematological Malignancies appearing as the primary indexed condition, and to 1 intervention — of which Talquetamab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04634552 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Other, New York, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04634552 about?
NCT04634552 is a clinical study titled "A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma". The purpose of this study is to evaluate the efficacy and safety of talquetamab in participants with relapsed or refractory multiple myeloma at the recommended Phase 2 dose(s) (RP2Ds) (Part 3).
What is the current status of trial NCT04634552?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 510 participants. The study started on 2021-02-01. Estimated completion is 2029-03-30.
What conditions does trial NCT04634552 study?
This clinical trial studies the following conditions: Hematological Malignancies. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04634552?
The interventions under investigation include: Talquetamab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04634552?
This trial is sponsored by Janssen Research & Development, which has 442 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04634552 being conducted?
This trial has 20 study locations across Alabama, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How Clinical Trials Work
Understand phases 1-4, trial design, randomization, and the informed consent process.
Patient Rights in Clinical Trials
Your rights as a participant: consent, withdrawal, privacy, and who to contact.
Finding the Right Clinical Trial
A practical guide to searching trials, understanding eligibility, and evaluating options.
All Guides
Browse our complete library of clinical trial educational resources.
Read our methodology — how this data is sourced, computed, and verified.