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NCT04557098 · ClinicalTrials.gov registry record · Phase 2
A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
A Phase 2 study of Hematological Malignancies, sponsored by Janssen Research & Development.
- Active
- Registry status
- Phase 2
- Development phase
- 194
- Enrollment target
- 20
- Study locations
NCT04557098: Active Phase 2 study of Hematological Malignancies, sponsored by Janssen Research & Development.
NCT04557098 is a Phase 2 study of Hematological Malignancies that is active but no longer recruiting, run by Janssen Research & Development. The registered enrollment target is 194 participants, below the 764-participant average among 16 other Hematological Malignancies trials with a reported enrollment target (75% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04557098, a Phase 2 study of Hematological Malignancies, is active but no longer recruiting, sponsored by Janssen Research & Development.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 194 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate the efficacy of teclistamab at the recommended Phase 2 dose (RP2D).
Primary Outcome
ORR is defined as the proportion of participants who have a partial response (PR) or better according to the International Myeloma Working Group (IMWG) criteria.
Conditions Studied
Interventions
- DRUG Teclistamab
Study Locations (20)
Other
- Universitair Ziekenhuis Gent - UZ GENT - Ghent
- Universitaire Ziekenhuizen Leuven - Leuven
- Peking University First Hospital - Beijing
- West China Hospital Si Chuan University - Chengdu
- Sun Yat -Sen University Cancer Center - Guangzhou
- First affiliated Hospital of Zhejiang University - Hangzhou
California
- City of Hope - Duarte
- University of California San Francisco - San Francisco
- Stanford University Medical Center - Stanford
New York
- Icahn School of Medicine at Mount Sinai Program for the Protection of Human Subjects - New York
- Memorial Sloan-Kettering Cancer Center - New York
Alberta
- Arthur J E Child Comprehensive Cancer Centre - Calgary
- Cross Cancer Institute - Edmonton
Alabama
- University of Alabama at Birmingham - Birmingham
Georgia
- Winship Cancer Institute Emory University - Atlanta
Michigan
- Barbara Ann Karmanos Cancer Institute - Detroit
North Carolina
- Levine Cancer Institute - Charlotte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 194 participants |
| Start Date | 2020-09-17 |
| Est. Completion | 2027-05-28 |
| Phase | Phase 2 |
What the registry record for NCT04557098 still lists
NCT04557098 is an interventional study that assigns participants to a tested intervention. The registered 194 participants enrollment target is mid-sized for trials with a published cap, below the 764-participant average among 16 other Hematological Malignancies trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Hematological Malignancies appearing as the primary indexed condition, and to 1 intervention - of which Teclistamab is the first listed.
NCT04557098 names 20 study sites across 11 states, led by Other, California, New York.
Frequently Asked Questions
What is clinical trial NCT04557098 about?
NCT04557098 is a clinical study titled "A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma". The purpose of this study is to evaluate the efficacy of teclistamab at the recommended Phase 2 dose (RP2D).
What is the current status of trial NCT04557098?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 194 participants. The study started on 2020-09-17. Estimated completion is 2027-05-28.
What conditions does trial NCT04557098 study?
This clinical trial studies the following conditions: Hematological Malignancies.
What interventions are being tested in trial NCT04557098?
The interventions under investigation include: Teclistamab (DRUG).
Who is sponsoring clinical trial NCT04557098?
This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04557098 being conducted?
This trial has 20 study locations across Alabama, California, Georgia, Michigan, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hematological Malignancies
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04557098's enrollment target sits among peer trials
194 6th of 16 higher than 11 of 16 other Hematological Malignancies trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hematological Malignancies trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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