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ClinicalTrials.gov 5 recruiting now official registry

Hematological Malignancies clinical trials

Every US clinical trial registered for Hematological Malignancies — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

17 US clinical trials · 5 currently recruiting

The research picture

Hematological Malignancies has 17 registered US clinical trials, 5 of them open to new participants right now — about 29% of the total.

5
recruiting participants now
29%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
4
top sponsor: Janssen Research & Development

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 10,000 participants

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

Dana-Farber Cancer Institute

NCT02269592

RECRUITING Phase 2 510 participants

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT04634552

RECRUITING Phase 1 420 participants

A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies

Daiichi Sankyo

NCT07220616

RECRUITING Phase 2 126 participants

Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

University of Nebraska

NCT06799195

RECRUITING Phase 1 36 participants

Safety and Efficacy of SMART101 in Pediatric and Adult Patients With Hematological Malignancies After T Cell Depleted Allo-HSCT

Smart Immune SAS

NCT04959903

ACTIVE NOT RECRUITING Phase 1 302 participants

Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT03145181

ACTIVE NOT RECRUITING Phase 1 279 participants

Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT03399799

ACTIVE NOT RECRUITING Phase 2 194 participants

A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT04557098

ACTIVE NOT RECRUITING Phase 1 56 participants

Study of AZD9829 in CD123+ Hematological Malignancies

AstraZeneca

NCT06179511

ACTIVE NOT RECRUITING Phase 1 50 participants

Durvalumab and Tremelimumab for Pediatric Malignancies

AstraZeneca

NCT03837899

ACTIVE NOT RECRUITING NA 20 participants

Feasibility of the Use of Weighted Blankets to Improve Sleep Among Patients With Hematological Malignancies

M.D. Anderson Cancer Center

NCT06584955

COMPLETED Phase 2 192 participants

A Study of Pembrolizumab/Vibostolimab (MK-7684A) in Relapsed/Refractory Hematological Malignancies (MK-7684A-004, KEYVIBE-004)

Merck Sharp & Dohme

NCT05005442

COMPLETED Phase 1 106 participants

Study of Tinostamustine, First-in-Class Alkylating HDACi Fusion Molecule, in Relapsed/Refractory Hematologic Malignancies

Mundipharma Research Limited

NCT02576496

COMPLETED 43 participants

The Good Patient Study

St. Jude Children's Research Hospital

NCT02199548

COMPLETED Phase 1 36 participants

Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM

Gamida Cell

NCT01816230

COMPLETED Phase 3 36 participants

Expanded Access of Omidubicel, for Allogeneic Transplantation in Patients With Hematological Malignancies

Gamida Cell

NCT04260698

COMPLETED Phase 1 17 participants

Compassionate Use Study of Tenalisib (RP6530)

Rhizen Pharmaceuticals

NCT03711604

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 4
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hematological Malignancies Trial Landscape

ClinicalTrials.gov lists 17 US studies indexed under Hematological Malignancies, and 5 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Hematological Malignancies shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Hematological Malignancies is led by Janssen Research & Development with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 17 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hematological Malignancies?

PlainTrial tracks 17 US clinical trials for Hematological Malignancies, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hematological Malignancies?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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