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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Hematological Malignancies: early-phase trial registry

5 of 17 indexed Hematological Malignancies trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 5 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Hematological Malignancies: 17 US clinical trials tracked, 5 recruiting.

Hematological Malignancies is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Janssen Research & Development, running 4 of these trials.

Enrollment posture brief

Registry condition hematological-malignancies

OPEN 5 | RECR 29% | LATE 1 | EARLY 13 | RANK #1004 | SPON 4

Nearest open-share peer: Addiction (29% recruiting · 17 trials)

Acute Myeloid Leukemia, in R70.6%Abdominal Aortic Aneurysm52.9%Hematological Malignanci (th…29%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Hematological Malignancies

Hematological Malignancies lists 5 open slots (29% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hematological Malignancies on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hematological Malignancies is recruiting below its size-band peers.

    5 of 17 indexed trials (29.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Hematological Malignancies research.

    Janssen Research & Development accounts for 4 of 17 trials (23.5%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Typical Hematological Malignancies enrolment sits around 106 participants.

    Median target enrolment is 106 among the 17 trials that report a genuine target (sentinel values excluded). 8 of those (47.1%) plan for fewer than 100 participants.

  4. Hematological Malignancies research is mostly interventional.

    15 interventional and 2 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 19Phase 24Phase 31

Open and recent trials

17 total, page 1 of 1

RECRUITING 10,000 participants

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

Dana-Farber Cancer Institute

NCT02269592

RECRUITING Phase 2 510 participants

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT04634552

RECRUITING Phase 1 420 participants

A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies

Daiichi Sankyo

NCT07220616

RECRUITING Phase 2 126 participants

Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

University of Nebraska

NCT06799195

RECRUITING Phase 1 36 participants

Safety and Efficacy of SMART101 in Pediatric and Adult Patients With Hematological Malignancies After T Cell Depleted Allo-HSCT

Smart Immune SAS

NCT04959903

ACTIVE NOT RECRUITING Phase 1 302 participants

Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT03145181

ACTIVE NOT RECRUITING Phase 1 279 participants

Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT03399799

ACTIVE NOT RECRUITING Phase 2 194 participants

A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development

NCT04557098

ACTIVE NOT RECRUITING Phase 1 56 participants

Study of AZD9829 in CD123+ Hematological Malignancies

AstraZeneca

NCT06179511

ACTIVE NOT RECRUITING Phase 1 50 participants

Durvalumab and Tremelimumab for Pediatric Malignancies

AstraZeneca

NCT03837899

ACTIVE NOT RECRUITING NA 20 participants

Feasibility of the Use of Weighted Blankets to Improve Sleep Among Patients With Hematological Malignancies

M.D. Anderson Cancer Center

NCT06584955

COMPLETED Phase 2 192 participants

A Study of Pembrolizumab/Vibostolimab (MK-7684A) in Relapsed/Refractory Hematological Malignancies (MK-7684A-004, KEYVIBE-004)

Merck Sharp & Dohme

NCT05005442

COMPLETED Phase 1 106 participants

Study of Tinostamustine, First-in-Class Alkylating HDACi Fusion Molecule, in Relapsed/Refractory Hematologic Malignancies

Mundipharma Research Limited

NCT02576496

COMPLETED 43 participants

The Good Patient Study

St. Jude Children's Research Hospital

NCT02199548

COMPLETED Phase 1 36 participants

Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM

Gamida Cell

NCT01816230

COMPLETED Phase 3 36 participants

Expanded Access of Omidubicel, for Allogeneic Transplantation in Patients With Hematological Malignancies

Gamida Cell

NCT04260698

COMPLETED Phase 1 17 participants

Compassionate Use Study of Tenalisib (RP6530)

Rhizen Pharmaceuticals

NCT03711604

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 4
Phase 3 1

Named interventions

Most-linked intervention names on Hematological Malignancies records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Talquetamab Drug
2 trials
Tinostamustine Drug
1 trials
Pembrolizumab/vibostolimab coformulation Biological
1 trials
omidubicel Biological
1 trials
Tenalisib Drug
1 trials
NiCord® Drug
1 trials
AZD9829 Drug
1 trials
Weighted Blanket Other
1 trials

US sites by state

Facility locations filed on Hematological Malignancies trials. A trial with sites in several states counts in each.

New York 10 trials
California 9 trials
North Carolina 5 trials
Texas 4 trials
Tennessee 4 trials
Ohio 4 trials
Michigan 4 trials
Illinois 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Hematological Malignancies page

17 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hematological Malignancies condition card totals 17 registered trials; most-linked intervention Talquetamab; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.