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Hematological Malignancies clinical trials
Every US clinical trial registered for Hematological Malignancies — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
17 US clinical trials · 5 currently recruiting
The research picture
Hematological Malignancies has 17 registered US clinical trials, 5 of them open to new participants right now — about 29% of the total.
- 5
- recruiting participants now
- 29%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Janssen Research & Development
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome
Dana-Farber Cancer Institute
NCT02269592
A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
Janssen Research & Development
NCT04634552
A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies
Daiichi Sankyo
NCT07220616
Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation
University of Nebraska
NCT06799195
Safety and Efficacy of SMART101 in Pediatric and Adult Patients With Hematological Malignancies After T Cell Depleted Allo-HSCT
Smart Immune SAS
NCT04959903
Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma
Janssen Research & Development
NCT03145181
Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
Janssen Research & Development
NCT03399799
A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
Janssen Research & Development
NCT04557098
Study of AZD9829 in CD123+ Hematological Malignancies
AstraZeneca
NCT06179511
Durvalumab and Tremelimumab for Pediatric Malignancies
AstraZeneca
NCT03837899
Feasibility of the Use of Weighted Blankets to Improve Sleep Among Patients With Hematological Malignancies
M.D. Anderson Cancer Center
NCT06584955
A Study of Pembrolizumab/Vibostolimab (MK-7684A) in Relapsed/Refractory Hematological Malignancies (MK-7684A-004, KEYVIBE-004)
Merck Sharp & Dohme
NCT05005442
Study of Tinostamustine, First-in-Class Alkylating HDACi Fusion Molecule, in Relapsed/Refractory Hematologic Malignancies
Mundipharma Research Limited
NCT02576496
The Good Patient Study
St. Jude Children's Research Hospital
NCT02199548
Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM
Gamida Cell
NCT01816230
Expanded Access of Omidubicel, for Allogeneic Transplantation in Patients With Hematological Malignancies
Gamida Cell
NCT04260698
Compassionate Use Study of Tenalisib (RP6530)
Rhizen Pharmaceuticals
NCT03711604
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 9 |
| Phase 2 | 4 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hematological Malignancies Trial Landscape
ClinicalTrials.gov lists 17 US studies indexed under Hematological Malignancies, and 5 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Hematological Malignancies shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Hematological Malignancies is led by Janssen Research & Development with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 17 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hematological Malignancies?
PlainTrial tracks 17 US clinical trials for Hematological Malignancies, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hematological Malignancies?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.