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NCT05164744 · ClinicalTrials.gov registry record
Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors
A clinical trial of COVID-19 and COVID-19 Respiratory Infection, sponsored by Weill Medical College of Cornell University.
- Recruiting
- Registry status
- 510
- Enrollment target
- 3
- Study locations
NCT05164744: Recruiting study of COVID-19 and COVID-19 Respiratory Infection, sponsored by Weill Medical College of Cornell University.
NCT05164744 is a study of COVID-19 and COVID-19 Respiratory Infection that is actively recruiting participants, run by Weill Medical College of Cornell University. The registered enrollment target is 510 participants, below the 38,463-participant average among 298 other COVID-19 trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05164744, a study of COVID-19 and COVID-19 Respiratory Infection, is actively recruiting participants, sponsored by Weill Medical College of Cornell University.
- RECRUITING
- Registry status
- 510 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to test if visualizing the heart with cardiac MRI/echo will be important in the understanding cardiac function and prediction of cardiopulmonary symptoms, physical effort tolerance, and outcomes in COVID-19 survivors. If successful, the research will allow us to identify the causes of lasting cardiopulmonary symptoms and begin developing cardiac and lung directed therapies accordingly.
Primary Outcome
Focal fibrosis scored on LGE(late gadolinium enhancement) CMR in affected LV segment based on transmural extent of hyperenhanced myocardium at \> 3 months post-COVID-19 diagnosis. Further categorized in accordance with established criteria (ischemic: subendocardial or transmural, non-ischemic: mid or epicardial). Total size (% LV myocardium) measured based on segmental scores, further quantified using the full-width half maximum method.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Cardiac MRI
- DIAGNOSTIC_TEST Echocardiogram
- DIAGNOSTIC_TEST 6-minute walk test
- DIAGNOSTIC_TEST Questionnaire
Study Locations (3)
New York
- New York Presbyterian-Brooklyn Methodist Hospital - Brooklyn
- New York Presbyterian Queens - New York
- Weill Cornell Medicine/New-York Presbyterian Hospital - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 510 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2026-07-30 |
What NCT05164744 shows while recruiting
NCT05164744 is an observational study that tracks outcomes without assigning an intervention. The registered 510 participants enrollment target is mid-sized for trials with a published cap, below the 38,463-participant average among 298 other COVID-19 trials with a reported enrollment target (99% lower).
The record links to 7 conditions, with COVID-19 appearing as the primary indexed condition, and to 4 interventions - of which Cardiac MRI is the first listed.
NCT05164744 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05164744 about?
NCT05164744 is a clinical study titled "Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors". The purpose of this study is to test if visualizing the heart with cardiac MRI/echo will be important in the understanding cardiac function and prediction of cardiopulmonary symptoms, physical effort tolerance, and outcomes in COVID-19 survivors. If successful, the research will allow us to identify...
What is the current status of trial NCT05164744?
This trial is currently recruiting. The enrollment target is 510 participants. The study started on 2021-07-01. Estimated completion is 2026-07-30.
What conditions does trial NCT05164744 study?
This clinical trial studies the following conditions: COVID-19, COVID-19 Respiratory Infection, COVID-19 Pneumonia, COVID-19 Acute Respiratory Distress Syndrome, Coronavirus Disease 2019.
What interventions are being tested in trial NCT05164744?
The interventions under investigation include: Cardiac MRI (DIAGNOSTIC_TEST), Echocardiogram (DIAGNOSTIC_TEST), 6-minute walk test (DIAGNOSTIC_TEST), Questionnaire (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05164744?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05164744 being conducted?
This trial has 3 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05164744's enrollment target sits among peer trials
510 108th of 298 higher than 191 of 298 other COVID-19 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other COVID-19 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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