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NCT05156112 · ClinicalTrials.gov registry record · NA
OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit
A NA study of Post Traumatic Stress Disorder and Obstructive Sleep Apnea, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 194
- Enrollment target
- 1
- Study location
NCT05156112: Recruiting NA study of Post Traumatic Stress Disorder and Obstructive Sleep Apnea, sponsored by VA Office of Research and Development.
NCT05156112 is a NA study of Post Traumatic Stress Disorder and Obstructive Sleep Apnea that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 194 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05156112, a NA study of Post Traumatic Stress Disorder and Obstructive Sleep Apnea, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 194 participants
- Enrollment target
- 1
- Study location
Study Summary
Substance use disorder (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur and having both disorders is associated with greater psychological and functional impairment than having either disorder alone. This is especially true in residential settings where both disorders are more severe than outpatient settings. Obstructive sleep apnea (OSA) is highly comorbid with both disorders and untreated OSA is associated with worse functional impairment across multiple domains, worse quality of life, worse PTSD, higher suicidal ideation, and higher substance use and relapse rates. Treating OSA with evidence-based positive airway pressure (PAP) in Veterans with SUD/PTSD on a residential unit is a logical way to maximize treatment adherence and treatment outcomes. This study compares OSA treatment while on a SUD/PTSD residential unit to a waitlist control group. The investigators hypothesize that treating OSA on the residential unit, compared to the waitlist control, will have better functional, SUD, and PTSD outcomes.
Primary Outcome
Change in functional impairment across multiple domains. The WHODAS 2.0 is a 36-item questionnaire that assess functional impairment across 5 subscales: cognitions (understanding and communicating), mobility, self-care getting along with others, household responsibilities, work responsibilities, and community participation.
Conditions Studied
Interventions
- DEVICE Positive Airway Pressure Device
Study Locations (1)
California
- VA San Diego Healthcare System, San Diego, CA - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 194 participants |
| Start Date | 2023-01-02 |
| Est. Completion | 2027-05-31 |
| Phase | NA |
What NCT05156112 shows while recruiting
NCT05156112 is an interventional study that assigns participants to a tested intervention. The registered 194 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (71% lower).
The record links to 4 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 1 intervention - of which Positive Airway Pressure Device is the first listed.
NCT05156112 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05156112 about?
NCT05156112 is a clinical study titled "OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit". Substance use disorder (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur and having both disorders is associated with greater psychological and functional impairment than having either disorder alone. This is especially true in residential settings where both disorders are more seve...
What is the current status of trial NCT05156112?
This trial is currently recruiting. It is a NA study. The enrollment target is 194 participants. The study started on 2023-01-02. Estimated completion is 2027-05-31.
What conditions does trial NCT05156112 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program.
What interventions are being tested in trial NCT05156112?
The interventions under investigation include: Positive Airway Pressure Device (DEVICE).
Who is sponsoring clinical trial NCT05156112?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05156112 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Traumatic Stress Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05156112's enrollment target sits among peer trials
194 58th of 262 higher than 205 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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