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Aphasia: early-phase trial registry
25 of 43 indexed Aphasia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #339 of 28,707 conditions by registered trial count.
43 US clinical trials · 25 currently recruiting · #339 of 28,707 conditions by registered trial count
Aphasia: 43 US clinical trials tracked, 25 recruiting.
Aphasia is the subject of 43 registered US clinical trials on ClinicalTrials.gov, 25 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Medical College of Wisconsin, running 5 of these trials.
Enrollment posture brief
Registry condition aphasia
OPEN 25 | RECR 58% | LATE 0 | EARLY 8 | RANK #339 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Cognitive Decline (58% recruiting · 62 trials)
Aphasia lists 25 open slots (58% of 43 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Aphasia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Aphasia is recruiting above its size-band peers.
25 of 43 indexed trials (58.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Aphasia trials is spread across many organizations.
Medical College of Wisconsin accounts for 5 of 43 trials (11.6%). 28 distinct sponsors appear on at least one study for this condition label.
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Most Aphasia trials plan to enrol fewer than 100 people.
Median target enrolment is 60 among the 43 trials that report a genuine target (sentinel values excluded). 29 of those (67.4%) plan for fewer than 100 participants.
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Aphasia research is mostly interventional.
39 interventional and 4 observational studies make up this index (90.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
43 total, page 1 of 1
ReadMap: Reading in Stroke Alexia and Typical Aging
Georgetown University
NCT06700005
Effects of Aphasia Identification Cards on Service Workers' Comprehension of People With Aphasia
University of Massachusetts, Amherst
NCT06990997
Language Processing and TMS
Medical College of Wisconsin
NCT05425615
tACS to Enhance Language Abilities
University of Pennsylvania
NCT06092814
Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia
University of Texas at Austin
NCT06511752
Aphasia Physical EXercise Study: Randomized Trial
University of California, Berkeley
NCT07281313
Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke
Medical College of Wisconsin
NCT06048159
Sentence Production Training in Aphasia
Purdue University
NCT05415501
Telerehabilitation for Aphasia (TERRA)
University of South Carolina
NCT04682223
Neural Bases of Vocal Sensorimotor Impairment in Aphasia
The University of Texas at Dallas
NCT04742894
Neuroplasticity Biomarkers in Aphasia
University of Wisconsin, Madison
NCT06471127
Escitalopram and Language Intervention for Subacute Aphasia
Johns Hopkins University
NCT03843463
Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
Kessler Foundation
NCT06213272
Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
Johns Hopkins University
NCT05845047
Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia
University of Pennsylvania
NCT06968663
Transcranial Alternating Current Stimulation (tACS) in Aphasia
Medical College of Wisconsin
NCT04375722
Treatment Outcomes With tDCS in Post-Stroke Aphasia
University of Arkansas
NCT03929432
Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
University of New Mexi
NCT04432883
Post-Stroke Aphasia TMS
Medical College of Wisconsin
NCT06974279
Effect of Community Choir Singing in People With Chronic Post-stroke Aphasia
University of Ottawa
NCT06368323
Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)
Teachers College, Columbia University
NCT07036406
Adaptive Trial Scheduling in Naming Treatment for Aphasia
University of Pittsburgh
NCT05653466
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
City University of New York
NCT04142866
Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia
University of Pittsburgh
NCT05653440
Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
University of Pennsylvania
NCT06842745
Brain-based Understanding of Individual Language Differences After Stroke
Georgetown University
NCT04991519
HD-tDCS for Phonological Impairment in Aphasia
Medical College of Wisconsin
NCT06010030
Genetic and Cognitive Predictors of Aphasia Treatment Response
Ohio State University
NCT05179538
Treatment for Speech and Language in Primary Progressive Aphasia
University of Texas at Austin
NCT04881617
Semantic Feature Analysis Treatment for Aphasia
VA Pittsburgh Healthcare System
NCT04215952
Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis
US Department of Veterans Affairs
NCT00125242
Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia
H. Branch Coslett
NCT03651700
NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery
Dr. Alexander Thiel
NCT02020421
The Intensive Comprehensive Aphasia Program (ICAP)
Shirley Ryan AbilityLab
NCT03514186
TMS as a Biological Marker of Neuroplasticity
University of Pennsylvania
NCT02867670
Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia
Georgetown University
NCT01709383
Intention Treatment for Anomia
VA Office of Research and Development
NCT04267198
Exercise Effects on Word Learning
VA Office of Research and Development
NCT03370471
Analysis of Brain Activity to Uncover Brain-behavior Relationships Related to Therapy Outcomes in Aphasia
Penn State University
NCT03550092
Adapting Acceptance and Commitment Therapy for Stroke Survivors With Aphasia
University of Pittsburgh
NCT04984239
Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia
University of California, Berkeley
NCT06185023
Inner Speech and Naming Treatment for Individuals with Aphasia
George Washington University
NCT05980897
Stroke-like Migraine Attacks After Radiation Treatment (SMART) Syndrome Language Intervention
Quality Living
NCT03662295
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 7 |
Top Sponsors
Named interventions
Most-linked intervention names on Aphasia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Aphasia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Aphasia page
43 registered trials, 25 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 25 Aphasia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Medical College of Wisconsin sponsors the most Aphasia trials on record, review their full trial history before evaluating a specific study. See Medical College of Wisconsin's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Aphasia condition card totals 43 registered trials; most-linked intervention Low-intensity physical exercise; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.