Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Aphasia
Open-data reference.
43 US clinical trials · 25 currently recruiting
Active & Recent Trials
ReadMap: Reading in Stroke Alexia and Typical Aging
Georgetown University
NCT06700005
Effects of Aphasia Identification Cards on Service Workers' Comprehension of People With Aphasia
University of Massachusetts, Amherst
NCT06990997
Language Processing and TMS
Medical College of Wisconsin
NCT05425615
tACS to Enhance Language Abilities
University of Pennsylvania
NCT06092814
Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia
University of Texas at Austin
NCT06511752
Aphasia Physical EXercise Study: Randomized Trial
University of California, Berkeley
NCT07281313
Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke
Medical College of Wisconsin
NCT06048159
Sentence Production Training in Aphasia
Purdue University
NCT05415501
Telerehabilitation for Aphasia (TERRA)
University of South Carolina
NCT04682223
Neural Bases of Vocal Sensorimotor Impairment in Aphasia
The University of Texas at Dallas
NCT04742894
Neuroplasticity Biomarkers in Aphasia
University of Wisconsin, Madison
NCT06471127
Escitalopram and Language Intervention for Subacute Aphasia
Johns Hopkins University
NCT03843463
Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
Kessler Foundation
NCT06213272
Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
Johns Hopkins University
NCT05845047
Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia
University of Pennsylvania
NCT06968663
Transcranial Alternating Current Stimulation (tACS) in Aphasia
Medical College of Wisconsin
NCT04375722
Treatment Outcomes With tDCS in Post-Stroke Aphasia
University of Arkansas
NCT03929432
Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
University of New Mexi
NCT04432883
Post-Stroke Aphasia TMS
Medical College of Wisconsin
NCT06974279
Effect of Community Choir Singing in People With Chronic Post-stroke Aphasia
University of Ottawa
NCT06368323
Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)
Teachers College, Columbia University
NCT07036406
Adaptive Trial Scheduling in Naming Treatment for Aphasia
University of Pittsburgh
NCT05653466
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
City University of New York
NCT04142866
Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia
University of Pittsburgh
NCT05653440
Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
University of Pennsylvania
NCT06842745
Brain-based Understanding of Individual Language Differences After Stroke
Georgetown University
NCT04991519
HD-tDCS for Phonological Impairment in Aphasia
Medical College of Wisconsin
NCT06010030
Genetic and Cognitive Predictors of Aphasia Treatment Response
Ohio State University
NCT05179538
Treatment for Speech and Language in Primary Progressive Aphasia
University of Texas at Austin
NCT04881617
Semantic Feature Analysis Treatment for Aphasia
VA Pittsburgh Healthcare System
NCT04215952
Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis
US Department of Veterans Affairs
NCT00125242
Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia
H. Branch Coslett
NCT03651700
NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery
Dr. Alexander Thiel
NCT02020421
The Intensive Comprehensive Aphasia Program (ICAP)
Shirley Ryan AbilityLab
NCT03514186
TMS as a Biological Marker of Neuroplasticity
University of Pennsylvania
NCT02867670
Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia
Georgetown University
NCT01709383
Intention Treatment for Anomia
VA Office of Research and Development
NCT04267198
Exercise Effects on Word Learning
VA Office of Research and Development
NCT03370471
Analysis of Brain Activity to Uncover Brain-behavior Relationships Related to Therapy Outcomes in Aphasia
Penn State University
NCT03550092
Adapting Acceptance and Commitment Therapy for Stroke Survivors With Aphasia
University of Pittsburgh
NCT04984239
Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia
University of California, Berkeley
NCT06185023
Inner Speech and Naming Treatment for Individuals with Aphasia
George Washington University
NCT05980897
Stroke-like Migraine Attacks After Radiation Treatment (SMART) Syndrome Language Intervention
Quality Living
NCT03662295
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 2 | 7 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Aphasia Trial Landscape
ClinicalTrials.gov lists 43 US studies indexed under Aphasia, and 25 of those are currently open to recruitment — roughly 58% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Aphasia shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Aphasia is led by Medical College of Wisconsin with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 43 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Aphasia?
PlainTrial tracks 43 US clinical trials for Aphasia, of which 25 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Aphasia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.