Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease

NCT03819153 · View on ClinicalTrials.gov ↗

Study Summary

The researchers are doing this study to see if semaglutide can slow down the growth and worsening of chronic kidney disease in people with type 2 diabetes. Participants will get semaglutide (active medicine) or placebo ('dummy medicine'). This is known as participants' study medicine - which treatment participants get is decided by chance. Semaglutide is a medicine, doctors can prescribe in some countries for the treatment of type 2 diabetes. Participants will get the study medicine in a pen. Participants will use the pen to inject the medicine in a skin fold once a week. The study will close when there is enough information collected to show clear result of the study. The total time participants will be in this study is about 3 to 5 years, but it could be longer.

Conditions Studied

Interventions

  • DRUG Semaglutide
  • DRUG Placebo (semaglutide)

Study Locations (20)

California

  • California Inst Of Renal Res — Chula Vista
  • John Muir Physician Network — Concord
  • John Muir Physicians Network — Concord
  • Valley Research — Fresno
  • California Institute of Renal Research — La Mesa
  • First Valley Med Grp Lancaster — Lancaster
  • Clinical Trials Research_Sacramento — Lincoln
  • VA Loma Linda Hlthcr Sys — Loma Linda
  • Long Beach Center For Clinical Research — Long Beach
  • VA Long Beach Healthcare System — Long Beach
  • Academic Medical Research Institute — Los Angeles
  • Valley Renal Medical Group Research — Northridge
  • Desert Oasis Hlthcr Med Group — Palm Springs
  • Saviers Medical Group — Port Hueneme
  • Inland Empire Clin Trials LLC — Rialto
  • Sierra Clinical Research — Roseville
  • California Research Foundation — San Diego
  • N America Res Inst - San Dimas — San Dimas
  • NorCal Endocrinology and Internal Medicine — San Ramon

Alabama

  • Dr. Terence Hart — Tuscumbia

Trial Details

FieldValue
Enrollment Target 3,533 participants
Start Date 2019-06-17
Est. Completion 2024-01-09
Phase Phase 3

Sponsor

Novo Nordisk A/S

189 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03819153

The ClinicalTrials.gov registry entry for NCT03819153 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,533 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 2 interventions — of which Semaglutide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03819153 reports 20 study locations spanning 2 distinct geographic areas — top geographies include California, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03819153 about?

NCT03819153 is a clinical study titled "A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease". The researchers are doing this study to see if semaglutide can slow down the growth and worsening of chronic kidney disease in people with type 2 diabetes. Participants will get semaglutide (active medicine) or placebo ('dummy medicine'). This is known as participants' study medicine - which treatme...

What is the current status of trial NCT03819153?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 3,533 participants. The study started on 2019-06-17. Estimated completion is 2024-01-09.

What conditions does trial NCT03819153 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03819153?

The interventions under investigation include: Semaglutide (DRUG), Placebo (semaglutide) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03819153?

This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03819153 being conducted?

This trial has 20 study locations across Alabama, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial