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NCT03377855 · ClinicalTrials.gov registry record · NA

Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients

A NA study of Opioid Use and Opioid-Related Disorders, sponsored by Weill Medical College of Cornell University.

Completed
Registry status
NA
Development phase
948
Enrollment target
2
Study locations

NCT03377855: Completed NA study of Opioid Use and Opioid-Related Disorders, sponsored by Weill Medical College of Cornell University.

NCT03377855 is a NA study of Opioid Use and Opioid-Related Disorders that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 948 participants, below the 148,251-participant average among 105 other Opioid Use trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03377855, a NA study of Opioid Use and Opioid-Related Disorders, has completed, sponsored by Weill Medical College of Cornell University.

COMPLETED
Registry status
NA
Development phase
948 participants
Enrollment target
2
Study locations

Study Summary

Risk of long-term opioid dependence increases with initial opioid dose/duration, but despite recent Centers for Disease Control and Prevention (CDC)-endorsed minimum doses for initial opioid prescription, primary care providers are likely to overprescribe. In this quality improvement project, primary care departments at Weill Cornell and the Institute for Family Health (federally qualified health center in New York City) will implement an unobtrusive "nudge" in their electronic prescribing software to promote the CDC-endorsed low doses for all opioids. In the evaluation, we will employ a quasi-experimental design with rigorous interrupted time series analysis methods to assess the effect of the "nudge" on prescribing rates. The analysis will be performed at the provider level, with deidentified physician data and a limited data set (fully deidentified except for date of prescription) of patient-level data.

Primary Outcome

Change in the proportion of opioid prescriptions for opioid-naïve patients that comply with CDC recommendations before and after the intervention

Conditions Studied

Opioid Use Opioid-Related Disorders Opioid Abuse Prescription Drug Abuse and Dependency

Interventions

  • OTHER Default Prescribing Change

Study Locations (2)

New York

  • The Institute for Family Health - New York
  • Weill Medical College of Cornell University - New York

Trial Details

FieldValue
Enrollment Target 948 participants
Start Date 2018-02-01
Est. Completion 2019-12-31
Phase NA
Weill Medical College of Cornell University

701 total trials

What the finished NCT03377855 record still lists

NCT03377855 is an interventional study that assigns participants to a tested intervention. The registered 948 participants enrollment target is mid-sized for trials with a published cap, below the 148,251-participant average among 105 other Opioid Use trials with a reported enrollment target (99% lower).

The record links to 4 conditions, with Opioid Use appearing as the primary indexed condition, and to 1 intervention - of which Default Prescribing Change is the first listed.

NCT03377855 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT03377855 about?

NCT03377855 is a clinical study titled "Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients". Risk of long-term opioid dependence increases with initial opioid dose/duration, but despite recent Centers for Disease Control and Prevention (CDC)-endorsed minimum doses for initial opioid prescription, primary care providers are likely to overprescribe. In this quality improvement project, primar...

What is the current status of trial NCT03377855?

This trial is currently completed. It is a NA study. The enrollment target is 948 participants. The study started on 2018-02-01. Estimated completion is 2019-12-31.

What conditions does trial NCT03377855 study?

This clinical trial studies the following conditions: Opioid Use, Opioid-Related Disorders, Opioid Abuse, Prescription Drug Abuse and Dependency.

What interventions are being tested in trial NCT03377855?

The interventions under investigation include: Default Prescribing Change (OTHER).

Who is sponsoring clinical trial NCT03377855?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03377855 being conducted?

This trial has 2 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Opioid Use

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03377855's enrollment target sits among peer trials

948 11th of 105 higher than 95 of 105 other Opioid Use trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Opioid Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT03377855, the US trial registry maintained by the National Library of Medicine. NCT03377855 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.