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ClinicalTrials.gov 4 recruiting now official registry

Opioid Abuse clinical trials

Every US clinical trial registered for Opioid Abuse — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

11 US clinical trials · 4 currently recruiting

The research picture

Opioid Abuse has 11 registered US clinical trials, 4 of them open to new participants right now — about 36% of the total.

4
recruiting participants now
36%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: University of Minnesota

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 480 participants

Rural Expanded Access to OUD Care & Linkage Using Toxicologists for Telehealth Initiated Treatment

Emory University

NCT05711056

RECRUITING 240 participants

fMRI and Opioid Abstinence

Yale University

NCT06651333

RECRUITING NA 30 participants

Neuromodulation and Cognitive Training in Opioid Use Disorder

University of Minnesota

NCT03773523

RECRUITING Phase 2 24 participants

Opioid/Benzodiazepine Polydrug Abuse: Aim 3

Wayne State University

NCT05006079

ACTIVE NOT RECRUITING NA 80 participants

Community Pharmacy-Based Prescription Drug Monitoring Program Opioid Risk Assessment Tool

University of Utah

NCT05706311

COMPLETED 15,438,284 participants

PCORnet Opioid Surveillance Study

Louisiana Public Health Institute

NCT03743493

COMPLETED NA 948 participants

Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients

Weill Medical College of Cornell University

NCT03377855

COMPLETED NA 631 participants

PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Opioid-Naive Population

University of Minnesota

NCT04601493

COMPLETED NA 62 participants

Cell Phone Technology Targeting ART Adherence and Drug Use

University of California, Los Angeles

NCT01884233

COMPLETED NA 42 participants

Opioid Education in Total Knee Arthroplasty

Hospital for Special Surgery, New York

NCT05593341

COMPLETED Phase 2 28 participants

Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers

New York State Psychiatric Institute

NCT01740414

Phase Distribution

PhaseTrial count
Phase 2 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Opioid Abuse Trial Landscape

ClinicalTrials.gov lists 11 US studies indexed under Opioid Abuse, and 4 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Opioid Abuse shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Opioid Abuse is led by University of Minnesota with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 11 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Opioid Abuse?

PlainTrial tracks 11 US clinical trials for Opioid Abuse, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Opioid Abuse?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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