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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Opioid Abuse: early-phase trial registry

4 of 11 indexed Opioid Abuse trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 4 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Opioid Abuse: 11 US clinical trials tracked, 4 recruiting.

Opioid Abuse is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 2 of these trials.

Enrollment posture brief

Registry condition opioid-abuse

OPEN 4 | RECR 36% | LATE 0 | EARLY 2 | RANK #1577 | SPON 2

Nearest open-share peer: Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (36% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%Opioid Abuse (this)36%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Opioid Abuse

Opioid Abuse lists 4 open slots (36% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Opioid Abuse on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Opioid Abuse is recruiting below its size-band peers.

    4 of 11 indexed trials (36.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Opioid Abuse research.

    University of Minnesota accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Opioid Abuse enrolment sits around 80 participants.

    Median target enrolment is 80 among the 11 trials that report a genuine target (sentinel values excluded). 6 of those (54.5%) plan for fewer than 100 participants.

  4. Opioid Abuse research is mostly interventional.

    9 interventional and 2 observational studies make up this index (81.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22

Open and recent trials

11 total, page 1 of 1

RECRUITING NA 480 participants

Rural Expanded Access to OUD Care & Linkage Using Toxicologists for Telehealth Initiated Treatment

Emory University

NCT05711056

RECRUITING 240 participants

fMRI and Opioid Abstinence

Yale University

NCT06651333

RECRUITING NA 30 participants

Neuromodulation and Cognitive Training in Opioid Use Disorder

University of Minnesota

NCT03773523

RECRUITING Phase 2 24 participants

Opioid/Benzodiazepine Polydrug Abuse: Aim 3

Wayne State University

NCT05006079

ACTIVE NOT RECRUITING NA 80 participants

Community Pharmacy-Based Prescription Drug Monitoring Program Opioid Risk Assessment Tool

University of Utah

NCT05706311

COMPLETED 15,438,284 participants

PCORnet Opioid Surveillance Study

Louisiana Public Health Institute

NCT03743493

COMPLETED NA 948 participants

Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients

Weill Medical College of Cornell University

NCT03377855

COMPLETED NA 631 participants

PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Opioid-Naive Population

University of Minnesota

NCT04601493

COMPLETED NA 62 participants

Cell Phone Technology Targeting ART Adherence and Drug Use

University of California, Los Angeles

NCT01884233

COMPLETED NA 42 participants

Opioid Education in Total Knee Arthroplasty

Hospital for Special Surgery, New York

NCT05593341

COMPLETED Phase 2 28 participants

Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers

New York State Psychiatric Institute

NCT01740414

Phase Distribution

PhaseTrial count
Phase 2 2

Named interventions

Most-linked intervention names on Opioid Abuse records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Text Messaging CBT (TXT-CBT) Behavioral
1 trials
PMP Integration & Nudge Behavioral
1 trials
Choice Architecture Nudge Behavioral
1 trials
Placebo First Drug
1 trials
MN-166 (50 mg) First Drug
1 trials
Default Prescribing Change Other
1 trials
Opioid education via video Other
1 trials
Opioid education in person Other
1 trials

US sites by state

Facility locations filed on Opioid Abuse trials. A trial with sites in several states counts in each.

New York 4 trials
Minnesota 2 trials
California 2 trials
Utah 1 trials
Pennsylvania 1 trials
Oregon 1 trials
Ohio 1 trials
Michigan 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Opioid Abuse page

11 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Opioid Abuse condition card totals 11 registered trials; most-linked intervention Text Messaging CBT (TXT-CBT); top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.