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NCT07357090 · ClinicalTrials.gov registry record · NA

Carbon Dioxide Administration and Brain Waste Clearance

A NA study of Traumatic Brain Injury and Aging Disorder, sponsored by Andrew Mayer.

Recruiting
Registry status
NA
Development phase
200
Enrollment target
1
Study location

NCT07357090 is a NA study of Traumatic Brain Injury and Aging Disorder that is actively recruiting participants, run by Andrew Mayer. The registered enrollment target is 200 participants, below the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (28% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07357090, a NA study of Traumatic Brain Injury and Aging Disorder, is actively recruiting participants, sponsored by Andrew Mayer.

RECRUITING
Registry status
NA
Development phase
200 participants
Enrollment target
1
Study location

Study Summary

The current study tests whether different exposures to carbon dioxide (CO2) can safely result in the increased movement of proteins from the brain into the blood. The investigators believe that this would be a proxy for the brain clearing waste products more effectively. The current study will use a counter-balanced design, in which individuals with and without a history of traumatic brain injury (TBI) will receive different levels of CO2 (targeted changes of approximately 5 or 10 mmHG in end-tidal CO2) approximately one week apart. The counter-balanced design means that each participant receives a single dose of CO2 at each visit, and different doses of CO2 at each visit. The order in which participants receive the dose is randomized, and the participant will not be informed of the dose.

Interventions

  • OTHER Hypercapnia task performed during fMRI

Study Locations (1)

New Mexico

  • The Mind Research Network - Albuquerque

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2026-04
Est. Completion 2032-02
Phase NA

Sponsor

Andrew Mayer

1 total trials

What the Registry Record Tells You About NCT07357090

The ClinicalTrials.gov registry entry for NCT07357090 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (28% lower). The listed sponsor is Andrew Mayer, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Traumatic Brain Injury appearing as the primary indexed condition, and to 1 intervention - of which Hypercapnia task performed during fMRI is the first listed.

NCT07357090 reports 1 study location spanning 1 distinct geographic area - top geographies include New Mexico.

Frequently Asked Questions

What is clinical trial NCT07357090 about?

NCT07357090 is a clinical study titled "Carbon Dioxide Administration and Brain Waste Clearance". The current study tests whether different exposures to carbon dioxide (CO2) can safely result in the increased movement of proteins from the brain into the blood. The investigators believe that this would be a proxy for the brain clearing waste products more effectively. The current study will use a...

What is the current status of trial NCT07357090?

This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2026-04. Estimated completion is 2032-02.

What conditions does trial NCT07357090 study?

This clinical trial studies the following conditions: Traumatic Brain Injury, Aging Disorder, Magnetic Resonance Imaging (MRI).

What interventions are being tested in trial NCT07357090?

The interventions under investigation include: Hypercapnia task performed during fMRI (OTHER).

Who is sponsoring clinical trial NCT07357090?

This trial is sponsored by Andrew Mayer, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07357090 being conducted?

This trial has 1 study location across New Mexico. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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