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NCT02553941 · ClinicalTrials.gov registry record · Phase 1
Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome
A Phase 1 study of Chronic Myelomonocytic Leukemia and Previously Treated Myelodysplastic Syndrome, sponsored by Brian Jonas.
- Completed
- Registry status
- Phase 1
- Development phase
- 21
- Enrollment target
- 5
- Study locations
NCT02553941 is a Phase 1 study of Chronic Myelomonocytic Leukemia and Previously Treated Myelodysplastic Syndrome that has completed, run by Brian Jonas. The registered enrollment target is 21 participants, below the 88-participant average among 73 other Chronic Myelomonocytic Leukemia trials with a reported enrollment target (76% lower). The trial reports 5 study locations across 1 state.
The verdict
NCT02553941, a Phase 1 study of Chronic Myelomonocytic Leukemia and Previously Treated Myelodysplastic Syndrome, has completed, sponsored by Brian Jonas.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 21 participants
- Enrollment target
- 5
- Study locations
Study Summary
This phase Ib trial studies the side effects and best dose of ibrutinib when given together with azacitidine in treating patients with myelodysplastic syndrome that is likely to occur or spread (higher risk) and who were previously treated or untreated and unfit for or refused intense therapy. Ibrutinib and azacitidine may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
Conditions Studied
Interventions
- DRUG Azacitidine
- DRUG Ibrutinib
Study Locations (5)
California
- UCLA / Jonsson Comprehensive Cancer Center - Los Angeles
- UC Irvine Health/Chao Family Comprehensive Cancer Center - Orange
- University of California Davis Comprehensive Cancer Center - Sacramento
- University of California San Diego - San Diego
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2016-05-17 |
| Est. Completion | 2019-11-07 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02553941
The ClinicalTrials.gov registry entry for NCT02553941 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 88-participant average among 73 other Chronic Myelomonocytic Leukemia trials with a reported enrollment target (76% lower). The listed sponsor is Brian Jonas, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Chronic Myelomonocytic Leukemia appearing as the primary indexed condition, and to 2 interventions - of which Azacitidine is the first listed.
NCT02553941 reports 5 study locations spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT02553941 about?
NCT02553941 is a clinical study titled "Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome". This phase Ib trial studies the side effects and best dose of ibrutinib when given together with azacitidine in treating patients with myelodysplastic syndrome that is likely to occur or spread (higher risk) and who were previously treated or untreated and unfit for or refused intense therapy. Ibrut...
What is the current status of trial NCT02553941?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2016-05-17. Estimated completion is 2019-11-07.
What conditions does trial NCT02553941 study?
This clinical trial studies the following conditions: Chronic Myelomonocytic Leukemia, Previously Treated Myelodysplastic Syndrome, de Novo Myelodysplastic Syndrome, Secondary Myelodysplastic Syndrome, Refractory Anemia With Excess Blasts in Transformation.
What interventions are being tested in trial NCT02553941?
The interventions under investigation include: Azacitidine (DRUG), Ibrutinib (DRUG).
Who is sponsoring clinical trial NCT02553941?
This trial is sponsored by Brian Jonas, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02553941 being conducted?
This trial has 5 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Chronic Myelomonocytic Leukemia
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