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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Previously Treated Myelodysplastic Syndrome: early-phase trial registry

4 of 10 indexed Previously Treated Myelodysplastic Syndrome trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 4 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Previously Treated Myelodysplastic Syndrome: 10 US clinical trials tracked, 4 recruiting.

Previously Treated Myelodysplastic Syndrome is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Fred Hutchinson Cancer Center, running 4 of these trials.

Enrollment posture brief

Registry condition previously-treated-myelodysplastic-syndrome

OPEN 4 | RECR 40% | LATE 0 | EARLY 10 | RANK #1724 | SPON 4

Nearest open-share peer: Acute Myeloid Leukemia (AML) (40% recruiting · 30 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Previously Treated Myelo (th…40%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Previously Treated Myelodysplastic Syndrome

Previously Treated Myelodysplastic Syndrome lists 4 open slots (40% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Previously Treated Myelodysplastic Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Previously Treated Myelodysplastic Syndrome is recruiting below its size-band peers.

    4 of 10 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Previously Treated Myelodysplastic Syndrome research.

    Fred Hutchinson Cancer Center accounts for 4 of 10 trials (40%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Typical Previously Treated Myelodysplastic Syndrome enrolment sits around 127 participants.

    Median target enrolment is 127 among the 10 trials that report a genuine target (sentinel values excluded). 4 of those (40%) plan for fewer than 100 participants.

  4. Previously Treated Myelodysplastic Syndrome research is mostly interventional.

    10 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 23

Open and recent trials

10 total, page 1 of 1

RECRUITING Phase 2 508 participants

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

M.D. Anderson Cancer Center

NCT02115295

RECRUITING Phase 2 140 participants

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

M.D. Anderson Cancer Center

NCT01624805

RECRUITING Phase 1 127 participants

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

Mayo Clinic

NCT03017820

RECRUITING Phase 1 30 participants

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

University of Chicago

NCT02333162

ACTIVE NOT RECRUITING Phase 1 54 participants

Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT02890329

COMPLETED Phase 2 210 participants

Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Fred Hutchinson Cancer Center

NCT00105001

COMPLETED Phase 1 199 participants

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Fred Hutchinson Cancer Center

NCT02044796

COMPLETED Phase 1 106 participants

Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer

Fred Hutchinson Cancer Center

NCT00027820

COMPLETED Phase 1 28 participants

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Fred Hutchinson Cancer Center

NCT02921061

COMPLETED Phase 1 21 participants

Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome

Brian Jonas

NCT02553941

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 3

Named interventions

Most-linked intervention names on Previously Treated Myelodysplastic Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fludarabine Phosphate Drug
3 trials
Filgrastim Biological
3 trials
Cytarabine Drug
3 trials
Laboratory Biomarker Analysis Other
3 trials
Cladribine Drug
3 trials
Allogeneic Hematopoietic Stem Cell Transplantation Procedure
2 trials
Cyclosporine Drug
2 trials
Peripheral Blood Stem Cell Transplantation Procedure
2 trials

US sites by state

Facility locations filed on Previously Treated Myelodysplastic Syndrome trials. A trial with sites in several states counts in each.

Washington 4 trials
Texas 3 trials
Georgia 3 trials
California 3 trials
Wisconsin 2 trials
Utah 2 trials
Arizona 2 trials
Virginia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Previously Treated Myelodysplastic Syndrome page

10 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Previously Treated Myelodysplastic Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Fred Hutchinson Cancer Center sponsors the most Previously Treated Myelodysplastic Syndrome trials on record, review their full trial history before evaluating a specific study. See Fred Hutchinson Cancer Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Previously Treated Myelodysplastic Syndrome condition card totals 10 registered trials; most-linked intervention Fludarabine Phosphate; top US site state Washington. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.