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NCT06071624 · ClinicalTrials.gov registry record · Phase 1
Chimeric Antigen Receptor T Cell Therapy Redirected to CD4 (CD4CAR)as a Second Line Treatment for Chronic Myelomonocytic Leukemia, CMML.
A Phase 1 study of Chronic Myelomonocytic Leukemia, sponsored by Huda Salman.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 4
- Study locations
NCT06071624 is a Phase 1 study of Chronic Myelomonocytic Leukemia that is actively recruiting participants, run by Huda Salman. The registered enrollment target is 30 participants, below the 88-participant average among 73 other Chronic Myelomonocytic Leukemia trials with a reported enrollment target (66% lower). The trial reports 4 study locations across 4 states.
The verdict
NCT06071624, a Phase 1 study of Chronic Myelomonocytic Leukemia, is actively recruiting participants, sponsored by Huda Salman.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 4
- Study locations
Study Summary
This study is designed as a single arm open label traditional Phase I, 3+3, study of CD4-directed chimeric antigen receptor engineered T-cells (CD4CAR) in subjects with relapsed or refractory CMML. Specifically, the study will evaluate the safety and feasibility of CD4CAR T-cells.
Conditions Studied
Interventions
- BIOLOGICAL CD4CAR
Study Locations (4)
Florida
- University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida 33136 - Miami
Indiana
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center - Indianapolis
New York
- Albert Einstein Health Network - The Bronx
Texas
- The University of Texas MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2024-02-21 |
| Est. Completion | 2043-12 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06071624
The ClinicalTrials.gov registry entry for NCT06071624 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 88-participant average among 73 other Chronic Myelomonocytic Leukemia trials with a reported enrollment target (66% lower). The listed sponsor is Huda Salman, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Chronic Myelomonocytic Leukemia appearing as the primary indexed condition, and to 1 intervention - of which CD4CAR is the first listed.
NCT06071624 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Florida, Indiana, New York.
Frequently Asked Questions
What is clinical trial NCT06071624 about?
NCT06071624 is a clinical study titled "Chimeric Antigen Receptor T Cell Therapy Redirected to CD4 (CD4CAR)as a Second Line Treatment for Chronic Myelomonocytic Leukemia, CMML.". This study is designed as a single arm open label traditional Phase I, 3+3, study of CD4-directed chimeric antigen receptor engineered T-cells (CD4CAR) in subjects with relapsed or refractory CMML. Specifically, the study will evaluate the safety and feasibility of CD4CAR T-cells.
What is the current status of trial NCT06071624?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2024-02-21. Estimated completion is 2043-12.
What conditions does trial NCT06071624 study?
This clinical trial studies the following conditions: Chronic Myelomonocytic Leukemia.
What interventions are being tested in trial NCT06071624?
The interventions under investigation include: CD4CAR (BIOLOGICAL).
Who is sponsoring clinical trial NCT06071624?
This trial is sponsored by Huda Salman, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06071624 being conducted?
This trial has 4 study locations across Florida, Indiana, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.