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COMPLETED Phase 2

Long-term Follow-up Study of GLPG0634 in Active Rheumatoid Arthritis Participants

NCT02065700 · View on ClinicalTrials.gov ↗

Study Summary

The primary objective of the study was to evaluate the long-term safety and tolerability of filgotinib (formerly GLPG0634) for the treatment of rheumatoid arthritis. Participants were enrolled in this open-label long-term follow-up study after they had completed one of the two core studies, GLPG0634-CL-203 (DARWIN1) (NCT01888874) or GLPG0634-CL-204 (DARWIN2) (NCT01894516), and were evaluated for any side effects that might have occured (long-term safety and tolerability) when taking filgotinib. During the course of the study, participants were also examined for long-term effects of filgotinib administration on disease activity (efficacy), participant's disability, fatigue, and quality of life.

Conditions Studied

Interventions

  • DRUG Filgotinib

Study Locations (20)

Other

  • Atencion Integral en Reumatologa — Buenos Aires
  • CER Intituto Medico — Buenos Aires
  • Organizacion Medica de Investigaciones (OMI) — Buenos Aires
  • Instituto Reumatologico Strusberg — Córdoba
  • CIMeL Centro dee Investigacion Medico Lanus — Lanús

Florida

  • RASF Clinical Research Center — Boca Raton
  • Millenium Research — Ormond Beach
  • Lovelace Scientific Resources — Venice

Arizona

  • Arthro, Arthritis Care & Research — Gilbert
  • Arizona Arthritis & Rheumatology Research PLLC — Mesa

California

  • C.V. Mehta MD Medical Corp. — Hemet
  • Desert Medical Advances — Palm Desert

Texas

  • Austin Rheumatology Research PA — Austin
  • Pioneer Research Solutions Inc — Houston

Illinois

  • Springfield Clinic — Springfield

Maryland

  • Klein and Associates MD, PA — Hagerstown

North Carolina

  • Physicians East — Greenville

Trial Details

FieldValue
Enrollment Target 739 participants
Start Date 2014-02-25
Est. Completion 2023-01-19
Phase Phase 2

Sponsor

Galapagos

7 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02065700

The ClinicalTrials.gov registry entry for NCT02065700 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 739 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Galapagos, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 1 intervention — of which Filgotinib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02065700 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Other, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02065700 about?

NCT02065700 is a clinical study titled "Long-term Follow-up Study of GLPG0634 in Active Rheumatoid Arthritis Participants". The primary objective of the study was to evaluate the long-term safety and tolerability of filgotinib (formerly GLPG0634) for the treatment of rheumatoid arthritis. Participants were enrolled in this open-label long-term follow-up study after they had completed one of the two core studies, GLPG063...

What is the current status of trial NCT02065700?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 739 participants. The study started on 2014-02-25. Estimated completion is 2023-01-19.

What conditions does trial NCT02065700 study?

This clinical trial studies the following conditions: Rheumatoid Arthritis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02065700?

The interventions under investigation include: Filgotinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02065700?

This trial is sponsored by Galapagos, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02065700 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial