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NCT02959463 · ClinicalTrials.gov registry record · Phase 1

Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma

A Phase 1 study of Pleural Malignant Mesothelioma, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
Phase 1
Development phase
24
Enrollment target
1
Study location

NCT02959463 is a Phase 1 study of Pleural Malignant Mesothelioma that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 24 participants, below the 61-participant average among 4 other Pleural Malignant Mesothelioma trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02959463, a Phase 1 study of Pleural Malignant Mesothelioma, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

This phase I trial studies the side effects and best way to give pembrolizumab after radiation therapy in treating patients with pleural malignant mesothelioma. Radiation therapy uses high energy radiation to kill tumor cells and shrink tumors. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving pembrolizumab after radiation therapy may kill more tumor cells.

Interventions

  • BIOLOGICAL Pembrolizumab
  • OTHER Laboratory Biomarker Analysis
  • RADIATION Radiation Therapy
  • RADIATION Palliative Radiation Therapy

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2017-05-01
Est. Completion 2028-12-31
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT02959463

The ClinicalTrials.gov registry entry for NCT02959463 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 61-participant average among 4 other Pleural Malignant Mesothelioma trials with a reported enrollment target (61% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pleural Malignant Mesothelioma appearing as the primary indexed condition, and to 4 interventions - of which Pembrolizumab is the first listed.

NCT02959463 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT02959463 about?

NCT02959463 is a clinical study titled "Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma". This phase I trial studies the side effects and best way to give pembrolizumab after radiation therapy in treating patients with pleural malignant mesothelioma. Radiation therapy uses high energy radiation to kill tumor cells and shrink tumors. Immunotherapy with monoclonal antibodies, such as pembr...

What is the current status of trial NCT02959463?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2017-05-01. Estimated completion is 2028-12-31.

What conditions does trial NCT02959463 study?

This clinical trial studies the following conditions: Pleural Malignant Mesothelioma.

What interventions are being tested in trial NCT02959463?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Laboratory Biomarker Analysis (OTHER), Radiation Therapy (RADIATION), Palliative Radiation Therapy (RADIATION).

Who is sponsoring clinical trial NCT02959463?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02959463 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.