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NCT02977780 · ClinicalTrials.gov registry record · Phase 2

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

A Phase 2 study of Glioblastoma, sponsored by Patrick Wen, MD.

Recruiting
Registry status
Phase 2
Development phase
460
Enrollment target
12
Study locations

NCT02977780 is a Phase 2 study of Glioblastoma that is actively recruiting participants, run by Patrick Wen, MD. The registered enrollment target is 460 participants, above the 107-participant average among 199 other Glioblastoma trials with a reported enrollment target (330% higher). The trial reports 12 study locations across 10 states.

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The verdict

NCT02977780, a Phase 2 study of Glioblastoma, is actively recruiting participants, sponsored by Patrick Wen, MD.

RECRUITING
Registry status
Phase 2
Development phase
460 participants
Enrollment target
12
Study locations

Study Summary

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM). The drugs involved in this study are : * Abemaciclib (arm is currently closed to accrual) * Temozolomide (temodar) * Neratinib (arm is currently closed to accrual) * CC115 (arm is currently closed to accrual) * QBS10072S

Conditions Studied

Interventions

  • DRUG Neratinib
  • DRUG Temozolomide
  • DRUG Abemaciclib
  • DRUG QBS10072S
  • DRUG CC-115

Study Locations (12)

Massachusetts

  • Massachusetts General Hospital - Boston
  • Dana Farber Cancer Institute - Boston

New York

  • Columbia University Medical Center - New York
  • Memorial Sloan Kettering Cancer Center - New York

Alabama

  • University of Alabama at Birmingham - Birmingham

Minnesota

  • Mayo Clinic - Rochester

Ohio

  • Cleveland Clinic - Cleveland

Pennsylvania

  • University of Pittsburgh Medical Center - Pittsburgh

Rhode Island

  • Lifespan / Rhode Island Hospital - Providence

Texas

  • UT MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 460 participants
Start Date 2017-02-09
Est. Completion 2028-04-30
Phase Phase 2

Sponsor

Patrick Wen, MD

2 total trials

What the Registry Record Tells You About NCT02977780

The ClinicalTrials.gov registry entry for NCT02977780 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 460 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 107-participant average among 199 other Glioblastoma trials with a reported enrollment target (330% higher). The listed sponsor is Patrick Wen, MD, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Glioblastoma appearing as the primary indexed condition, and to 5 interventions - of which Neratinib is the first listed.

NCT02977780 reports 12 study locations spanning 10 distinct geographic areas - top geographies include Massachusetts, New York, Alabama.

Frequently Asked Questions

What is clinical trial NCT02977780 about?

NCT02977780 is a clinical study titled "INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)". This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM). The drugs involved in this study are : * Abemaciclib (arm is currently closed to accrual) * Temozolomide (temodar) * Neratinib (arm is currently closed to accrual) * CC115 (arm is currentl...

What is the current status of trial NCT02977780?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 460 participants. The study started on 2017-02-09. Estimated completion is 2028-04-30.

What conditions does trial NCT02977780 study?

This clinical trial studies the following conditions: Glioblastoma.

What interventions are being tested in trial NCT02977780?

The interventions under investigation include: Neratinib (DRUG), Temozolomide (DRUG), Abemaciclib (DRUG), QBS10072S (DRUG), CC-115 (DRUG).

Who is sponsoring clinical trial NCT02977780?

This trial is sponsored by Patrick Wen, MD, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02977780 being conducted?

This trial has 12 study locations across Alabama, Massachusetts, Minnesota, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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