Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00380445 · ClinicalTrials.gov registry record · Phase 3

Effect of Vildagliptin on Fat and Muscle Metabolism in Patients With Type 2 Diabetes

A Phase 3 study of Diabetes Mellitus, Type 2, sponsored by Novartis.

Completed
Registry status
Phase 3
Development phase
21
Enrollment target
2
Study locations

NCT00380445: Completed Phase 3 study of Diabetes Mellitus, Type 2, sponsored by Novartis.

NCT00380445 is a Phase 3 study of Diabetes Mellitus, Type 2 that has completed, run by Novartis. The registered enrollment target is 21 participants, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (100% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00380445, a Phase 3 study of Diabetes Mellitus, Type 2, has completed, sponsored by Novartis.

COMPLETED
Registry status
Phase 3
Development phase
21 participants
Enrollment target
2
Study locations

Study Summary

Please note this study is not being conducted in the United States. The purpose of this study is to test the hypothesis that acute DPP-4 inhibition with vildagliptin improves fat and muscle metabolism in patients with type 2 diabetes mellitus.

Conditions Studied

Interventions

  • DRUG Vildagliptin

Study Locations (2)

New Jersey

  • Novartis Pharmaceuticals - East Hanover

Other

  • Novartis Investigative Site - Investigative Centers

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2006-01
Est. Completion 2007-04
Phase Phase 3
Novartis

265 total trials

What the finished NCT00380445 record still lists

NCT00380445 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (100% lower).

The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 1 intervention - of which Vildagliptin is the first listed.

NCT00380445 reports a single indexed study location in New Jersey, Other.

Frequently Asked Questions

What is clinical trial NCT00380445 about?

NCT00380445 is a clinical study titled "Effect of Vildagliptin on Fat and Muscle Metabolism in Patients With Type 2 Diabetes". Please note this study is not being conducted in the United States. The purpose of this study is to test the hypothesis that acute DPP-4 inhibition with vildagliptin improves fat and muscle metabolism in patients with type 2 diabetes mellitus.

What is the current status of trial NCT00380445?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 21 participants. The study started on 2006-01. Estimated completion is 2007-04.

What conditions does trial NCT00380445 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2.

What interventions are being tested in trial NCT00380445?

The interventions under investigation include: Vildagliptin (DRUG).

Who is sponsoring clinical trial NCT00380445?

This trial is sponsored by Novartis, which has 265 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00380445 being conducted?

This trial has 2 study locations across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes Mellitus, Type 2

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00380445's enrollment target sits among peer trials

21 323rd of 348 higher than 26 of 348 other Diabetes Mellitus, Type 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes Mellitus, Type 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02447874 · 21 participants · Phase 1

    Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease

  • NCT03826992 · 21 participants · Phase 1

    Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

  • NCT04107077 · 21 participants · Phase 2

    Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer

  • NCT04158635 · 21 participants · Phase 1

    Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00380445, the US trial registry maintained by the National Library of Medicine. NCT00380445 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.