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NCT00357578 · ClinicalTrials.gov registry record
Genetic Study of Age-Related Macular Degeneration
A clinical trial of Age-related Macular Degeneration, sponsored by National Eye Institute (NEI).
- Completed
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT00357578 is a study of Age-related Macular Degeneration that has completed, run by National Eye Institute (NEI). The registered enrollment target is 150 participants, below the 1,506-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00357578, a study of Age-related Macular Degeneration, has completed, sponsored by National Eye Institute (NEI).
- COMPLETED
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine skin and blood cells for genetic changes related to the development of age-related macular degeneration, an eye disease that can significantly impair the ability to read, drive, and carry out daily activities. It is the most common cause of vision loss in people over the age of 50. People with age-related macular degeneration and healthy normal volunteers age 50 years or older may be eligible for this study. Candidates will undergo a medical history, physical examination and eye examination with dilation of the pupils. Photographs of the eye will be taken with a special camera. Study participants will have blood drawn three times (no more than 6 tablespoons each time) and will undergo three skin biopsies. For the skin biopsy, an anesthetic is injected under the skin and a small piece of skin-approximately 1/4-inch cube-is removed. The blood draws and biopsies will be done at 7- to 10-day intervals. In most cases, a single biopsy is done at each visit, but it may be necessary to take-at most-one additional biopsy from the other arm during the same visit. Patients will return for one follow-up visit 7 to 10 days after the last biopsy for examination of the biopsy site and removal of any stitches. The results of this study may provide investigators information needed to develop new means of diagnosing and treating age-related macular degeneration.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2000-04-14 |
| Est. Completion | 2007-09-19 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00357578
The ClinicalTrials.gov registry entry for NCT00357578 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,506-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (90% lower). The listed sponsor is National Eye Institute (NEI), which has 221 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Age-related Macular Degeneration appearing as the primary indexed condition, and to 0 interventions.
NCT00357578 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00357578 about?
NCT00357578 is a clinical study titled "Genetic Study of Age-Related Macular Degeneration". This study will examine skin and blood cells for genetic changes related to the development of age-related macular degeneration, an eye disease that can significantly impair the ability to read, drive, and carry out daily activities. It is the most common cause of vision loss in people over the age ...
What is the current status of trial NCT00357578?
This trial is currently completed. The enrollment target is 150 participants. The study started on 2000-04-14. Estimated completion is 2007-09-19.
What conditions does trial NCT00357578 study?
This clinical trial studies the following conditions: Age-related Macular Degeneration.
Who is sponsoring clinical trial NCT00357578?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00357578 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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