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NCT01973309 · ClinicalTrials.gov registry record · Phase 1
A Study of Vantictumab (OMP-18R5) in Combination With Paclitaxel in Locally Recurrent or Metastatic Breast Cancer
A Phase 1 study, sponsored by OncoMed Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 37
- Enrollment target
NCT01973309: Completed Phase 1 study, sponsored by OncoMed Pharmaceuticals.
NCT01973309 is a Phase 1 study that has completed, run by OncoMed Pharmaceuticals. The registered enrollment target is 37 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (38% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01973309, a Phase 1 study, has completed, sponsored by OncoMed Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 37 participants
- Enrollment target
Study Summary
This is an open-label Phase 1b dose-escalation study to assess the safety, tolerability, and PK of vantictumab when combined with paclitaxel.
Primary Outcome
The maximum tolerated dose (MTD) will be determined in patients treated with vantictumab in combination with paclitaxel
Interventions
- DRUG Vantictumab combined with paclitaxel
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2013-09 |
| Est. Completion | 2017-12 |
| Phase | Phase 1 |
What the finished NCT01973309 record still lists
NCT01973309 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (38% lower).
The record links to 0 conditions, and to 1 intervention - of which Vantictumab combined with paclitaxel is the first listed.
NCT01973309 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01973309 about?
NCT01973309 is a clinical study titled "A Study of Vantictumab (OMP-18R5) in Combination With Paclitaxel in Locally Recurrent or Metastatic Breast Cancer". This is an open-label Phase 1b dose-escalation study to assess the safety, tolerability, and PK of vantictumab when combined with paclitaxel.
What is the current status of trial NCT01973309?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2013-09. Estimated completion is 2017-12.
What interventions are being tested in trial NCT01973309?
The interventions under investigation include: Vantictumab combined with paclitaxel (DRUG).
Who is sponsoring clinical trial NCT01973309?
This trial is sponsored by OncoMed Pharmaceuticals, which has 25 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01973309's enrollment target sits among peer trials
37 1204th of 2000 higher than 791 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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